Meta-analysis Of Risk Factors Of Complications For Colorectal Cancer After Laparoscopic Colorectal Resection

ObjectiveThe overall purpose of this research is to explore clinical risk factors of complications after laparoscopic surgery for colorectal cancer patients and provide preventive measures.MethodsResearches on the risk factors of complications after laparoscopic surgery for colorectal cancer patients in Chinese or English from January 2010 to November 2015 were searched and analysis.Data were evaluated by odds ratio(OR) and 95% confidence interval(95%CI).ResultsTotally 8 studies including 2021 patients were incorporated and analyzed. In which,404 cases developed postoperative complications,and the incidence was 18.30%.The result from Meta-analysis showed that 7 demographic factors were significantly related to increasing the incidence of postoperative complications,including male gender(OR=1.55,95%CI:1.24~1.94,P=0.000<0.05),age(OR=0.40,95%CI:0.18~0.86,P=0.020<0.05),nutritional status(OR=4.10,95%CI:1.89~8.89,P=0.000<0.05),concurrent pulmonary diseases(OR=2.69,95%CI:1.57~4.62,P=0.000<0.05),concurrent diabetes mellitus(OR=1.61,95%CI:1.09~2.35,P=0.015<0.05),operation types(OR=0.66,95%CI:0.46~0.95,P=0.025<0.05),operation time(OR=0.44,95%CI:0.22~0.88,P=0.020<0.05).However,BMI,hypertension,cardiopathy,conversion,tumor size and tumor stage were not related to complications.ConclusionThe occurrence of postoperative complications in laparoscopic surgery for colorectal tumor are associated with male gender, age, nutritional status,concurrent pulmonary diseases, concurrent diabetes mellitus, operation types, operation time.