| Objective:To analyze dietary fiber on the impact of postoperative inflammatory response in patients with gastrointestinal malignancy.Methods:Fifty-eight cases of gastrointestinal malignancy patients who came from the First Hospital of Shanxi Medical University, were included in this experiment from September 1,2015 to February 28 2016. Fifty-eight patients were randomized to be divided into experimental group(TPF group, n=29) and controlled group(TP group, n=29). After operation, enteral nutrition and parenteral nutrition were applied to two groups of patients for next 7 days. Experimental group received TPF, control group received TP. Peripheral Blood samples were observed in the 1st day before operation and in the 2nd and 8th day after operation respectively to measure about inflammatory response indicators(WBC, N and CRP) and immune indexes(Ig A, Ig M, Ig G, CD4%, CD8% and CD4/CD8).Results:Compared experimental group with control group, all the preoperative detection indexes were not significantly different(p> 0.05). All the inflammatory response indicators of the 2nd day after operation(WBC, N and CRP) were higher than the 1st day before operation, and reached statistical significance(P <0.05), but two groups were not significantly different(p> 0.05). Compared with control group in the 8th day after operation,all the inflammatory response indicators(WBC, N and CRP) of experimental group were lower(P <0.05).All the immune indexes(Ig A, Ig M, Ig G, CD4%, CD8%) of two groups in the 2nd after operation have decreased to some extent, but not reached statistical significance in addition to Ig G(p> 0.05). Compared to the control group in the 2nd day after operation, Ig G, CD4% and CD4 / CD8 of experimental group have a more significant rise(p <0.05).Conclusion:Dietary fiber can enhance immunity and reduce postoperative acute inflammatory response in patients with gastrointestinal malignancy. |
PDF Full Text Request