Synthesis Of Benzimidazole Derivative, Its Iridium (Ⅲ) Complex And Their Applications In Ion Detection

Both metal ions and anions play very import role in the environment, medicine and biochemistry. However excess or deficiency of them in organism can lead many diseases. Thus, monitoring kinds and concentration of these ions in biological or environmental samples is particularly important because of their adverse influence for biological health. Compared with the traditional ion analysis and testing technology （inductively coupled plasma-atomic emission spectrometry, electrochemical sensing, atomic absorption spectrometry and so on）, photochemical sensor has attracted considerable interest owing to their low detection limit, real-time detection, operational simplicity and high sensitivity. This thesis has reported a simple fluorescent probe with high selectivity and suitable affinity toward Cu+/Cu²⁺ based on fluorescence quenching mechanism. And its Cationic Iridium（Ⅲ） Complexes can recognise Cr3+ and F-. The main studies as follows:Chapter one is about the meaning of ion detection, conventional detection method of ion and photochemical sensor test which has developed rapidly in recent years. Mainly introduced the research status of some ions fluorescent chemosensors and F- phosphorescence chemosensors.In chapter two, we have presented a simple fluorescent chemosensor with high selectivity and suitable affinity toward Cu+/Cu²⁺ based on fluorescence quenching mechanism. It can display an excellent fluorescence "turn-off response to Cu+/Cu²⁺ over other common metal ions in aqueous media. And the visible quenching result from Cu+/Cu²⁺ can be applied to the detection of Cu+/Cu²⁺ by the naked eye. Moreover, confocal microscopy experiments indicate that it can be used for detecting Cu+/Cu²⁺ levels within living cells, this is meaningful in biomedical research.In chapter three, we have designed a new iridium（Ⅲ） complex which can recognise Cr3+ over other competing ions based on phosphorescence quenching mechanism. And the complex can also detect F- as a ratiometric and colorimetric phosphorescence chemosensor. To the best of our knowledge, this is the first iridium（Ⅲ） complex with multiple detection properties for Cr3+ and F- by different phenomenon.