Syntheses,Condition Optimizations And Thermodynamic Properties Of Two Types Of Green Bactericides

Traditional bactericides such as inorganic chlorine bactericide,aldehyde bactericide,iodine bactericide have the disadvantages of irritating smell,unstability,toxic side effects and so on.So exploring new types of green environment-friendly bactericides has been the unremitting pursue goal of the scientists.As new types of bactericides,percarbamide and 8-hydroxyquinoline copper have been widely used in pesticide,medicine,antibacterial,and other fields due to their excellent biological and pharmacological activities.These two kinds of compounds have been favored by safety,high efficiency,low toxicity,broad spectrum,etc.Percarbamide has potential value in cancer treatment,plant growth,medical oxygen,catalysis,biological engineering,and other fields;and 8-hydroxyquinoline complexes have potential applications in luminescent materials,cancer treatment and catalysis,etc.So,the study on Improving their product yields,purities and investigating on their thermal stabilities become one of the hot spot of current research.In this thesis,by the method of four factors and three levels,we investigated the optimal synthesis conditions of percarbamide and 8-hydroxyquinoline copper,and their structures and thermodynamic properties were studied.1.The method of four factors and three levels was used to study the influences of material ratio,reaction temperature,reaction time and stabilizer type in order to obtain the optimal process condition of percarbamide.The yield was 98.8%.process conditions:n(urea):n(hydrogen peroxide)=0.65:1,temperature 40 ℃,reaction time 40 min,and tartaric acid as stabilizer.The content of active oxygen was 17.5%.process conditions:n(urea):n(hydrogen peroxide)=0.75:1,temperature 30 ℃,reaction time 40 min,trimeric pyrazole borate as stabilizer.The thermal stability of percarbamide was investigated by thermal analysis.The result showed contents of oxygen and percarbamide declined rapidly when the temperature exceeded 65 ℃.The crystal structure was determined by X-ray diffraction,and described its three-dimensional supramolecular structure and the connection mode of hydrogen bond initially.2.The method of four factors and three levels was used to study the influences of 8-hydroxyquinoline concentration,temperature,time and pH in order to obtain the optimal process condition of 8-hydroxyquinoline copper.8-hydroxyquinoline copper yield was 97%.Process conditions:8-hydroxy quinoline concentration 0.4mol/L,reaction temperature 60 ℃,reaction time 3h,pH=9-10.The morphology of 8-hydroxyquinoline copper molecule was observed by SEM.In order to explore the storage conditions of 8-hydroxyquinoline copper,the thermal stability of the 8-hydroxyquinoline copper was also studied.And the measured copper 8-hydroxyquinoline molecule size was 20μm x 10μm.The chemical property of 8-hydroxyquinoline copper was very stable during heating.The quality change of 8-hydroxyquinoline copper was the fastest in the second hour,and the quality of the 8-hydroxyquinoline copper in the later period changed slowly.When the time is more than 14 hours,the quality of the 8-hydroxyquinoline copper remains the same.In the same time,the quality of 8-hydroxyquinoline copper was decreased with the increase of temperature.