Biological Reduction Research Of Penicillin Fermentation Residue

Antibiotics bacterial residue,which is a special kind of hazardous waste,has large production and potential environmental risk.Thus the rational and effective treatment methods for antibiotics bacterial residue have become the constraints of the pharmaceutical industry development.Biological reduction of penicillin fermentation residue was carried out in this study,in which penicillin fermentation residue was biological reduced successively by thermophilic bacteria,anaerobic digestion and photosynthetic bacteria.The experimental results were as follows:1)The results of biological reduction of penicillin fermentation residue by thermophilic bacteria showed that,under the condition of 1.0 kg COD/?m³·d?of penicillin bacteria residue organic load,60°C of the processing temperature,120 r/min of the speed,5% of the thermophilic bacteria concentration,7.0 of pH value,and 120 h of the reaction time,the decrement rate of TSS concentration reached to 40.49%.The SCOD concentration increased from 949 mg/L to 1726 mg/L.The results of dissolved cell reduction by ions showed that with 200 ?mol·L^-1of Na⁺ concentration,the decrement rate of TSS concentration reached to 56.75%,which increased by 15.96%.2)The results of anaerobic digestion of original penicillin bacteria residue,residue after the reduction by thermophilic bacteria,and residue strengthening by metal ions for30 d showed that,under the condition of 0.30 g VS/?L·d?of organic load,the TSS decrement rate and cumulative production of biogas of the residue strengthened by Na⁺ was enhanced by 26.29% and 46.70% more than the original sample,respectively.The average concentration of NH₃-N was 1 234.28 mg/L,which had no inhibition effect on the anaerobic digestion system.3)The results of biological reduction of biogas residue for 14 d by photosynthetic bacteria showed that,under the condition of 0.3 kg COD/?m³·d?of organic load,30% of the photosynthetic bacteria concentration,30°C of the processing temperature,7.0 of pH value,and intermittent light?12h 3000 Lx + 12 h none?,the TSS decrement rate of biogas residue was 67.80% after 8 d.4)The TSS decrement rate of penicillin fermentation residue could reach to 91.40%by three-level biological reduction successively with thermophilic bacteria,anaerobicdigestion and photosynthetic bacteria.