Synergistic Effect Of Microwave-Fenton-Activated Carbon On The Removal Of Berberine Hydrochloride In Water

With the pace of globalization,at the same time,the rapid economic and social development,,a large number of new drugs in the pharmaceutical field,including berberine hydrochloride.Its emergence is of great significance to the disease,at the same time,it also brings new challenges to the field of environmental protection.Berberine hydrochloride?C20H18NO4?is common in the pharmaceutical industry,usually in the case of yellow needle crystal or powder,odorless,bitter taste.Berberine hydrochloride was taking after the in vivo absorption rate is low,the unabsorbed berberine hydrochloride in vitro migration through discharge,in the environment of transformation into the aquatic environment,coupled with the industrial production of berberine hydrochloride can produce large amounts of waste water containing berberine hydrochloride into the water environment,the water environment in the growth of many microorganisms will be affected by the inhibition of berberine hydrochloride was even eliminated,a large part of living in the water caused by microbes in the environment have a serious influence on the process of growth and reproduction,thus destroying the circulation and the integrity of the food chain,the balance of the ecological system and ecological system;at the same time,in the environment of organism the accumulation and transfer along the food chain,which may induce drug resistance gene,spread and diffusion in the environment,human health and food and drink Water security is a serious threat,especially in recent years,the emergence of super bacteria has become a medical problem.However,there are few reports on the removal of the wastewaterAt present,the main technology of berberine hydrochloride wastewater treatment is the chemical method,including Fenton oxidation,catalytic wet air oxidation technology is a hotspot of current research,however,the single use of advanced oxidation technology to deal with berberine hydrochloride wastewater,not only the processing efficiency is low,and the high cost of processing.Nowadays,biological control has played an important role in the field of environmental pollution control.The application of biological method to treat berberine hydrochloride wastewater shows good prospects for development and application.However,when high concentrations of berberine hydrochloride wastewater can sterilization,low concentration time and bacteria,so it is difficult to use a single biological method tosolve the pollution problem of berberine hydrochloride wastewater obviously,therefore,combined with physical and chemical method and biological method for treatment of acid yellow element wastewater is the most promising method.At the same time,because the microwave has the ability of strong penetrating effect,because it can be directly heated in the reactant molecules,the activation of molecular chemical bond strength and the reaction system can be changed at the same time,the use of activated carbon with Fenton as catalyst,the reaction activity is greatly enhanced,so as to achieve better removal effect.In order to solve the problem of similar pharmaceutical wastewater removal,this paper provides a technical reference for the simulation of berberine hydrochloride wastewater treatment.Were used to separate individual microwave,activated carbon,Fenton reagent,Fenton-alone in conjunction with activated carbon,microwave activated carbon-Fenton-technology combined with five methods of removal of berberine hydrochloride,were investigated on the removal effect of Berberine Hydrochloride by different methods,and the effect of microwave time,microwave power,activated carbon dosing quantity and humic acid dosage,Fe²⁺ dosage,H₂O₂ dosage on the removal rate of berberine hydrochloride,and sodium hydroxide,sulfuric acid,sodium chloride,sodium silicate on activated carbon modified effect.Finally determine berberine hydrochloride solution of certain concentration,the optimum removal conditions of berberine hydrochloride was determined by orthogonal experiment,the biodegradability and explore the conditions of Berberine Hydrochloride Residue,and is in accordance with the first-order kinetic model.Results show:The single microwave technology has no effect on the removal of berberine hydrochloride,and the activated carbon technology and the Fenton technology are time-consuming and low in efficiency.The removal efficiency of Fenton-activated carbon technology was higher than that of single technology,and the removal efficiency of Berberine Hydrochloride by microwave-Fenton-activated carbon was much higher than that of other technologies.With the increase of the initial concentration of berberine hydrochloride in the solution,the removal rate decreased;increase of activated carbon dosage,the removal rate increased and then decreased;hydrogen peroxide concentration,humic acid concentration,dosage of Fe²⁺ continuously increased,showing the whole basic increases and then tends to decline.However,with the increase of microwave timeand microwave power,the removal rate of berberine hydrochloride was increased.The optimal removal condition of berberine hydrochloride was obtained by orthogonal experiment.The six factor of three was determined.The optimal removal conditions of berberine hydrochloride: humic acid 0.008g/L,Fe²⁺ 0.41g/L,0.7 g of activated carbon,microwave power 700 W,microwave time 5min,H₂O₂ 6mol/L,the removal rate reached 86.47% under the condition of berberine hydrochloride.According to the above optimum conditions,the residue of the best removal condition was obtained through the experiment.The results showed that the BOD/COD value of the residue was 0.353 and the TOC/TN value was 101.65,which was considered to be a certain degree of biodegradability.