Study On Preparation Of OS-?-CD/Curcumin Inclusion Complex And Its Application In Pickering Emulsion

Cyclodextrin can be modified by esterification reaction to improve its emulsifying ability,so it can be used to prepare Pickering emulsion.In this study,OS-?-CD were prepared,taking ?-CD and octenyl succinic anhydride as raw materials.The formation,thermodynamic property and appearance of OS-?-CD were confirmed by the results of FT-IR,XRD,1HNMR,and SEM;solubility,particle size,surface tension,interfacial tension and activation index were tested.The results showed that solubility,particle size,surface tension,interfacial tension of OS-?-CD decreased compared with ?-CD,but activation index increased.OS-?-CD with different DS were prepared to form emulsions,particle size,zeta potential,creaming index and the influence of pH,ionic strength and temperature on emulsion were studied.OS-?-CD with higher DS had better emulsifying ability.With the increase of DS,droplet size and zeta potential of Pickering emulsion decreased.After treatment of different pH,temperature,emulsion stabilized by OS-?-CD were still stable,while emulsions under the condition of different ionic strength were unstable.The formation,thermodynamic property and appearance of OS-?-CD/curcumin inclusion complexes were confirmed by the results of FT-IR,XRD,1HNMR,DSC,SEM and CLSM.FT-IR spectrum of inclusion complex suggested peak of curc?min at 1602 cm-1 and 1281 cm-1disappeared,and peak at 1153 cm-1was weaken,which suggested curcumin reacted with OS-?-CD.XRD showed that OS-?-CD/curcumin inclusion complex was V crystal structure.The results of DSC curve indicated that OS-?-CD/curcumin inclusion complex had new material melting peak and decomposition peak,the melting peak of curcumin and the decomposition peak of OS-?-CD disappeared.The results of SEM showed that photos of OS-?-CD/curcumin inclusion complex was different from that of OS-?-CD and curcumin,it was smooth and neat with edges;spherical particles were more apparent.CLSM showed the pictures of OS-?-CD/curcumin inclusion complex could be observed with the red and green fluorescent material,green part existed in the middle of red fluorescence.These results suggested that OS-?-CD really reacted with curcumin and the curcumin presented in the cavity of the OS-?-CD.Emulsions stabilized by OS-?-CD and OS-?-CD/curcumin inclusion complex were investigated,the influence of loading form of curcumin on oxidation stability was studied.The results of particle size,particle size distribution,zeta potential and creaming index showed that OS-?-CD/curcumin inclusion complex stabilized emulsions had good physical stability.Antioxidant study included primary oxidation product and secondary oxidation product,which showed OS-?-CD/curcumin inclusion complex stabilized emulsions had good chemical stability.Curcumin at the interface of oil and water had better antioxidant effect than curcumin in fish oil.