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Summarize Suxia Yang’’s Academic Experience And Clinical Research For Treating Liver Disease

Posted on:2017-04-20Degree:MasterType:Thesis
Country:ChinaCandidate:W B XuFull Text:PDF
GTID:2334330485455716Subject:Internal medicine of traditional Chinese medicine
Abstract/Summary:PDF Full Text Request
This paper mainly through two parts of basic theory and clinical research, summed up the academic thought and clinical experience of Yang Suxia director of diagnosis and treatment of liver disease. The most research value and the most representative disease of chronic hepatitis B and non alcoholic liver disease were studied in two liver diseases.Part 1 experience summaryObjective :Summarizing the academic thought and clinical experience of Yang Suxia on treating liver diseaseMethods: By collecting a large number of outpatient medical records(cases include the patient’s chief complaint, present illness, past medical history, symptoms and signs, and Yang’s diagnosis, treatment, medication and other information). The experience of the diagnosis and treatment of liver disease was recorded in the process of clinical diagnosis and treatment, Taking these as the foundation of the study of Yang Suxia’s academic thought, to summarize Yang Suxia’s experience in the diagnosis and treatment of chronic hepatitis B and non alcoholic fatty liver.Results: Yang Suxia proposed that we need to prevent the disease and prevent the development of the disease. She pay attention to the function of liver, spleen and kidney in the development of disease. She have two treatment thought, so-called attack refers to remove liver evil and complement to invigorating the spleen and kidney loss. At the same time she stressed the importance of health care for the prognosis of liver disease.Yang Suxia think nonalcoholic fatty liver multi section due to diet, do as one pleases food fat and sweet food, life of ease, caused by lack of exercise or its metabolic abnormalities and other factors. Pathogenesis is phlegm blocking, qi stagnation and blood stasis, the disease mainly in the liver and spleen two dirty and bile palace.Treatment with soothing the liver and invigorating the spleen, Qi and removing blood stasis method, put forward "of the liver and spleen be treated together internal and external coherence" "attack" "both qi and blood" of the rule. Under the influence of the Xin’an School of thought of“ wen bu pei yuan”, Yang improve the function of spleen using Codonopsis pilosula and Astragalus membranaceus, good warming middle Jiao and spleen qi. In the treatment of non alcoholic fatty liver, she have own experience,pinellia, dried orange peel, Arisaema cum bile, Poria, Atractylodes, Radix Codonopsis,astragalus, bupleurum, radix curcumae, hawthorn, peach kernel, red sage root, cassia seed, lotus leaf basic decoction, with Gynostemma pentaphyllum and Kuding tea bubble tea. The party mainly by strengthening spleen, resolving phlegm, accompanied with soothing the liver, activating blood circulation and to a sub clover with lipid-lowering,combination of internal and external, rigorous structure. The prescription is clever.Part 2 experience summaryObjective : Evaluate Yang Suxia’s experience in treating NAFLD. Analysis Yang Suxia’s experience in the diagnosis and treatment of CHB through data mining.Methods: 1.Collecting 60 cases of NAFLD patients who met the inclusion criteria in the Yang Suxia clinic in Chinese Medicine Hospital of Anhui province from September2013 to September 2015. According to the method of random number table, the patients were randomly divided into treatment group and control group, 30 cases in each group.The two group patients were treated with lifestyle intervention, such as diet, moderate aerobic exercise, fasting spicy fatigue and stay up. The treatment group patients taking experience prescription by two times one day. The control group patients taking Polyene Phosphatidylcholine Capsules three times a day and taking two pills one time.Treatment courses were 3 months, and we statistical effect after 3 months.2. We collected 111 effect cases of CHB. Patients’ basic information, medical record information, diagnosis, syndrome type, traditional Chinese medicine prescription, drugs and other information were recorded in the data acquisition system ETLV2.1, and then we process the date.Result: 1. This study collected 111 cases of effective cases, a total of 117 visits. There are 77 men and 34 women. Men are more than women. The oldest man is 89 years old,the youngest man is 25 years old, and the average age is 49.52 years old. There are six people between 25 to 30 years old, and the proportion is 5.1%. There are 23 people between 31 to 40 years old, and the proportion is 19.7%. There are 39 people between41 to 50 years old, and the proportion is 33.3%. There are 28 people between 41 to 50 years old, and the proportion is 23.9%. There are 14 people between 41 to 50 years old,and the proportion is 12.0%. There are 14 people between 41 to 50 years old, and the proportion is 12.0%. There are 14 people whose age are more than 70 years old, and the proportion is 6.0%.The age of patients with chronic hepatitis B is mainly concentrated in the age of 30 to 70 years.2. TCM syndrome types appear frequency from high to low ranked in the top six are Liver stagnation and spleen deficiency, Liver kidney yin deficiency syndrome,Phlegm stagnation syndrome,Damp heat syndrome of liver and gallbladder,Qi stagnation and blood stasis,Syndrome of disharmony between liver and stomach.3. Symptoms which appear more than ten times from high to low are fatigue,abdominal discomfort, diarrhea, restless sleep, rib discomfort, anorexia, dry mouth,chest tightness, dizziness, irritability. 4. A total of 167 traditional Chinese medicines were used in this study. There are 46 kinds of traditional Chinese medicine are used more than ten times. There are 7 kinds of traditional Chinese medicine are used more than 50 times.From high to low are liquorice, poria, atractylodes, tangerine peel, radix curcumae, dandelion, yam. There are five Traditional Chinese medicine which frequency in 30 to 50 times,from high to low are white peony root, bupleurum root,perilla stem, mother of pearl, coix seed; There are ten Traditional Chinese medicine which frequency in 20 to 30 times, from high to low are pinellia tuber, Radix Paeoniae rubra, Rhizoma Cyperi, Radix Codonopsis, Radix Angelicae sinensis, radix salviae miltiorrhizae, oriental wormwood, Radix Glehniae, astragalus, hanging pots of grass.There are 24 Traditional Chinese medicine which frequency in 10 to 20 times,from high to low are hawthorn, kudzu root, Poria, Radix Pseudostellariae, millet sprouts, Rhizoma Corydalis, malt, windproof, Ganoderma lucidum, white lentils, Cortex Moutan,chicken’s gizzard skin, Radix notoginseng, cuttlebone, polygala root, Rhizoma Chuanxiong, five sub flavor, Zhejiang Fritillaria, mint, ophiopogon root, Caulis Polygoni Multiflori, Perrin, Hedyotis diffusa Willd, bergamot. We obtained 4 groups of drug pairs and 2 drug group.The 4 group of drug were germinatus and malt, dandelion and perilla stem, cuttlebone and fritillary, dangshen and huangqi. The other 2 group are bupleurum, Radix Curcumae and Radix Paeoniae Alba, yam, Poria, Atractylodes,licorice, dried tangerine peel. We conclude that the disease is mainly distributed in the liver, spleen, stomach and kidney. The main pathological factors were dampness, Qi,blood stasis and deficiency. The main pathogenesis is Qi stagnation, blood stasis, spleen deficiency and dampness. The symptoms are weakness, anorexia, restless sleep, rib discomfort, diarrhea, belching. Miss Yang mainly use soothing liver, invigorating the spleen, regulating qi, and stomach, nourishing Yin, dampness of six kinds of method in the treatment of chronic hepatitis B. Doctor Yang usually use tonic, Qi, dampness, and blood stasis in treating chronic hepatitis B.After comprehensive analysis, we come to the core of the basic composition, bupleurum, radix curcumae, tangerine peel, Poria,Atractylodes, Chinese yam, white peony root, dandelion, perilla stem, mother of pearl,coix seed, licorice, a total of 12 kinds of drugs.
Keywords/Search Tags:the old Chinese medicine, liver disease, basic theory, experience summary, old Chinese medicine, fatty liver, chronic hepatitis B, empirical formula, data mining
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