Research Progress Of Postprandial Hypotension

Postprandial hypotension(PPH) is an important clinical syndrome, which occures commonly in the elderly. In addition, it is also common in patients with hypertension, diabetes, Alzheimer’s disease, Parkinson. There were also differences in the incidence of postprandial hypotension in different groups. There are three definitions of PPH: 1. a decrease in the systolic blood pressure at the does of 20 mmHg or above 2. the postprandial blood pressure is less than 90 mmHg when the preprandial blood pressure is higher than or equal to 100 mmHg within 2 hours 3. the emergence of symptoms of ischemic symptoms, such as dizziness, syncope, etc, although the drop degree of postprandial systolic blood pressure did meet the above standard. PPH onset occult, which leads to a series of serious ischemic events of cardiac and cerebral vessels, is a risk factor for cardiovascular events in the elderly. The pathogenesis of PPH involves multiple factors, including splanchna blood pool, dietary composition, gastric dilatation, gastric emptying rate, changes of gastrointestinal hormones, autonomic nervous dysfunction, etc. The risk factors of PPH include age, body mass index, history of cerebral vascular disease, high level of office blood pressure. These factors, as a predictor of PPH, is conducive to the identification of high-risk groups of PPH. Management of PPH includes ‘nonpharmacologic’ and ‘pharmacologic’. It is not sure whether these interventions can be widely used in patients with PPH.