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Combining Traditional Chinese And Western Medicine Treatment Of Threatened Abortion And Its Effect On PIBF Regulating Of Maternal Fetal Immune Tolerance

Posted on:2017-03-11Degree:MasterType:Thesis
Country:ChinaCandidate:K K WangFull Text:PDF
GTID:2334330491460301Subject:Gynecology of traditional Chinese medicine
Abstract/Summary:PDF Full Text Request
Objective:Through the intervention treatment of threatened abortion patients of kidney deficiency type given to the combination of Shoutai Pills addition and subtraction and dydrogesterone,at the same time the control group given to dydrogesterone,and contasting them, the curative effct of the combining traditional Chinese and western medicine treatment of threatened abortion was observed and the variation of progesterone-induced blocking factor(progesterone-induced blocking factor,PIBF) in maternal serum was monitored. The effect of the combining traditional Chinese and western medicine treatment of threatened abortion to the mechanism of maternal fetal immune tolerance was explored.Methods: 60 patients who conformed to the diagnosis standard in according to the random number table method divided into two groups,the observation group of 30 cases and the control group of 30 cases. The observation group was treated with the daily dose of Shoutai Pill addition and subtraction(free fried granule)with water and dydrogesterone 20 mg daily for two weeks. The control group received daily oral administration of progesterone 20 mg, for 2 weeks. Comprehensive effect of disease and syndrome curative effect of traditional Chinese medicine were compared between the observation group and the control group. Syndrome scores of traditional Chinese medicine and PIBF、estrodiol(estrodiol,E2)、progesterone(progesterone,P)、β-human chorionic gonadotropin(β-human chorionic gonadotropin,β-HCG) in the Peripheral blood serum treatment were compared between the observation group and the control group before and after treatment. correlation between average inner diameter、β-HCG and the PIBF in the peripheral blood in the observation group and the control group were observed.Results:1.The syndrome scores of traditional Chinese medicine of the observation group after treatment are lower than the syndrome scores of traditional Chinese medicine of the observation group before treatment and the control group. There are significant difference(P<0.5).2. PIBF、E2、P、β-HCG in the Peripheral blood serum of the observation group after treatment is significantly improved compared with the control group. There are significant difference(P<0.5).3.There is a positive correlation between the average inner diameter、β-HCG and PIBF in the peripheral blood(0<r<1).Conclusion: Given the combination of Shoutai Pills addition and subtraction and dydrogesterone to threatened abortion patients of kidney deficiency type can significantly improve the symptoms of threatened abortion.The treatment can increase PIBF、E2、P、β-HCG in the Peripheral blood serum and improve luteal function.It can significantly improve the maternal fetal immune tolerance.
Keywords/Search Tags:Shoutai Pills addition and subtraction, dydrogesterone, threatened abortion, PIBF, maternal fetal immune tolerance
PDF Full Text Request
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