Clinical Study With SWI On The Correlation Between Cerebral Microbleeds With Hemoglobin A1c In Type 2 Diabetes Mellitus

Purpose: To investigate the correlation between cerebral microbleeds witn hemoglobin A1 c in Type 2 Diabetes Mellitus use SWI.Methods: Collected the patients from the The First Affiliated Hospital, University of South China during January 2015 to January 2016 outpatient and hospitalization with type 2 diabetes. 57 patients with type 2 diabetes were divided into two groups according to the hemoglobin A1 c. 34 cases of men, women in 23 cases. All patients with conventional magnetic resonance imaging(MRI) and magnetic sensitive weighted sequence(SWI)scan. The brain is divided into cortex-subcortical, basal ganglia-brain stem, and the tent of meeting under the three, respectively in three cerebral microbleeds in the brain to count, according to the number of cerebral microbleeds in the brain is divided into four levels, level 0 = no cerebral microbleeds; Level 1=1-2; Level 2=3-10; level 3= cerebral microbleeds is more than 10. And between the two groups and micro total cerebral hemorrhage in the group count and glycosylated hemoglobin were compared between the two groups and each partition between cerebral microbleeds in the group classification and glycosylated hemoglobin were analyzed.Results: SWI sequence is the most effective inspection method to detecte the cerebral microbleeds in the brain with very high sensitivity and specificity; Cerebral microbleeds were appeared in the brain cortex-subcortical areas to level 2-3 in T2 DM, and basal ganglia-brain stem areas with 0 level, and act under the main usualy with 0 level; Between cerebral microbleeds with HbA1 c in the brain cortex-subcortical area, basal ganglia-brain stem area has certain correlation(P < 0.05), the tent of meeting under the there was no significant correlation(P > 0.05); CMBs diagnostic performance of HbA1 c in the basal ganglia-brain stem area and combined in the basal ganglia-brain stem area has certain diagnostic efficiency with high specificity.Conclusion: Magnetic resonance imaging(MRI) SWI sequence can be used as the first choice in check cerebral microbleeds; CMBs can predicted HbA1 c control level in patients with T2 DM, especially in the basal ganglia-brain stem, that have certain specificity; HbA1 c levels can predict the risk of brain cerebral microbleeds and severe degree; CMBs classification and judgment of the partition of long-term blood sugar control effect to provide a certain basis in patients with T2 DM.