Clinical Significance Of Tp-Tec、QTc And Tp-Te/QT Ratio On Occurrence Of The Pathological Ventricular Arrhythmia In Chronic Heart Failure Patients

Objective:To explore the clinical significance of Tp-Tec(corrected Tp-Te)、 QTc corrected QT)and Tp-Te/QT ratio on occurrence of the pathological ventricular arrhythmia in chronic heart failure patients.Methods:According to the strict inclusion and exclusion criterias,brought into 30 patients with chronic heart from our hospital as CHF group.And they were separated into two groups depending on ventricular arrhythmia or not.one group included of 15 cases having ventricular arrhythmia called Group A,and the other 15 cases wihout ventricular arrhyythmia was called Group B.20 cases of heathy people from our hostipal at the same period were selected as nonmal control group, a group C.All the patients were asked to do the examination of the conventional 12 lead synchronous ECG and 24 hours of dynamic elecrtocardiogram analysis at the first they came to hospital. Measure the Tp-Te interval、QT interval and R-R interval from a appropriate lead to get the Tp-Tec interval、QTc interval and Tp-Te/QT ratio. Compare and analyze the relationshiop between the change of these indexes and the occurrence of the ventricular arrhythmia in chronic heart failure patients. Results: After the comparing,we got that:(1)the contrast between CHF group and nonmal control group:The Tp-Tec interval、QTc interval and Tp-Te/QT ratio of CHF group were significantly higher than those of the nonmal control group.The difference was statisticdally significant(P<0.05).(2)the contrast among the three groups:The Tp-Tec interval、QTc interval and Tp-Te/QT ratio of the group A were significantly higher than the nonmal control group,s.The difference was statisticdally significant(P<0.05).The measurments of the group B were significantly higher than those of the nonmal control group,too.The difference was statisticdally significant(P<0.05).And in 30 cases of patients with chronic heart failure,these indexes of the group A were higher than group B.The difference of the Tp-Tec interval and Tp-Te/QT ratio were statisticdally significant(P<0.05).However,there was no significant difference about the QTc between the two groups(P>0.05). Conclusions: The Tp-Tec interval、QTc interval、Tp-Te/QT ration are related to the incidence of ventricular arrhythmia in the chronic heart failure patients,especially the Tp-Tec interval and Tp-Te/QT ratio.When the indexes enlarge, the tenency of the ventricular arrhythmia is higher,and there is predictive value to the onset of malignant arrhythmia, which has important clinical significance.