| Objective: At present, cardiovascular and cerebrovascular disease gradually become influence human health and life safety of an important risk factor, the in a variety of common diseases and multiple disease occupies very important position. And with the trend of aging population in China, the incidence of the disease will show a rapid growth rate, in which atherosclerosis is the leading cause of the disease. Therefore, it is possible to use effective indicators for the diagnosis of the disease, early discovery of problems, as soon as possible for the treatment of the patient’s overall disease development has a very important inhibitory effect. So the paper analysis the correlation between high sensitivity C reactive protein with atherosclerosis, to hope can through human serum high-sensitivity C- reactive protein content determination can effectively analysis in patients with atherosclerosis development and subsequent treatment to provide effective guidance.Methods: This study selected during June December 2014 to 2015 in outpatient and inpatient 100 cases of patients with atherosclerosis as the observation group. In the same period of healthy and 100 patients with atherosclerosis and infection immunity disease as control group. Basic survey of all patients, the study of statistical records of their hypertension, diabetes and smoking, drinking and other bad habits of life.Two groups of patients with age range, the sex ratio is almost the same and whose average age, basic disease data by statistical software for analysis can be that there is little difference between the two groups of patients, no statistical significance(P >0.05), the comprehensive comparison between all patients to compare.Result:1.The results of the study show that the serum FIB levels in patients in the observation group, LDL-C and t-CHY content of significantly higher than the patients in the control group. After statistical analysis can be drawn from the two groups compared with significant difference, and the difference is statistically significant(P < 0.05).2. After statistical analysis, two groups of subjects can come to the conclusion that the larger the difference, with very significant statistical significance(P < 0.05). To observe the average IMT in the group of subjects can reach(1.15 + 2.03) mm,significantly higher than the control group of patients with the average IMT value,compared to the two groups have very significant differences, with statistical significance. After the detection of serum high-sensitivity CRP can draw on high-sensitivity C-reactive protein(hs CRP) content in patients in the observation group has a very significant improvement, can be as high as(+ 5.78 2.04) mg / L,was significantly higher than that in the control group in the research object, the two groups compared with the very significant differences, there was statistically significant(P < 0.05).3.Research results show that the three groups of patients with serum hs CRP and IMT,TG, FIB, LDL-C content and the content of t-HCY exist the very big difference, after the relevant statistics of the statistical analysis that related differences between the three groups of patients was statistically significance(P < 0.05).Conclusion: 1. High sensitivity C reactive protein is a can effectively reflect the severity of carotid atherosclerosis in patients with and atherosclerotic plaque stability properties markers by of venous blood of patients with serum high-sensitivity C reactive protein content determination to related acute atherosclerotic disease made effective prediction and treatment and effective mitigation of the further deterioration of the patient’s condition, provide important guidance role and significance for the subsequent treatment.2.The severity of the high sensitive C reactive protein in patients with good effect of.Increased C-reactive protein levels in patients with venous serum HS C, said the inflammatory reaction occurred in patients with more and more strong, indicating that the higher the degree of atherosclerosis in patients with critical illness is more.This may explain the high sensitivity C reactive protein as the basic conditions of an inflammatory reaction medium can make effective reflection of the basic condition of patients and the prognosis. |
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