Relationship Between Air Pollution And Daily Death Of Cardiovascular Diseases In Hefei: A Time-Series Analysis

Objective: To analyze the effect of acute exposure to air pollutants(SO2,NO2,PM10)on daily death of cardiovascular diseases in Hefei.Methods: The data of daily death of cardiovascular diseases,the data of daily concentration of main air pollutants(SO2,NO2,PM10)and weather conditions(daily temperature,wind speed,air pressure and relative humidity)in Hefei from 2010 to 2015 were collected.For the analysis of relationship between air pollutants and daily death of cardiovascular diseases,the time series generalized additive model was fitted,after adjustments for time trends,”days of the week” effect and weather conditions.Results: Daily average concentrations of SO2,NO2,PM10 in Hefei from 2010 to 2015 were 20.58 ? g/m3,30.93 ? g/m3,105.91?g/m3.The concentration of PM10 was more than the second grade standard of GB3095-2012 Ambient Air Quality Standard.The number of death of cardiovascular diseases during the study in Hefei was 21816.In the single-pollutant models,an increase of 10 ? g/m3 of SO2,PM10 corresponded to an increase of2.27%(RR=1.02274,95%CI:1.00779~1.03791),0.407%(RR=1.00407,95%CI:1.00140~1.00674)of daily death of cardiovascular diseases,affected the daily death most evidently after 4 days and 0 day.NO2 had no obvious effects on daily death of cardiovascular diseases(P>0.05).In the multiple-pollutants models,the effects of SO2 and PM10 on daily death of cardiovascular diseases were less than that in the single-pollutant models after adjustments for other pollutants.Conclusion: Air SO2,PM10 of present level have an adverse effect on the daily death of cardiovascular diseases in Hefei.The daily concentration of NO2 is not associated with the daily death statistically.