Study On Syndrome Element Distribution Of Different Pathological Types And The Correlations With Anxiety And Depression Status In Chronic Atrophic Gastritis

Objective:Study on syndrome element distribution of different pathological types,atrophy,intestinal metaplasia and intraepithelial neoplasia and the correlations with anxiety and depression status in chronic atrophic gastritis,so as to provide guidance for clinical syndrome differentiation and treatment of the disease.Methods:95 patients with different pathological stages of CAG were collected from Fujian Universty of Traditional Medicine attached Second People Hospital which using the on-site questionnaire investigation in this study,four diagnostic information collection table,as well as Hamilton anxiety and depression scale were further completed;and then,identification of syndrome elements was conducted by health status identification system;thirdly,anxiety and depression scale were statistically classified;finally,the relationship between anxiety and depression in different pathological stages of CAG was investigated through statistical analysis.Results:1.There was no significant difference in gender and age distribution of CAG in different pathological types,but the distribution of age was predominated by middle-aged and elderly population,with an average age of(52.54± 10.18)years old.2.Distribution characteristics of CAG syndrome:syndrome elements of disease location was dominated by stomach,liver,spleen and kidney,and also involved heart and mind,gallbladder,lung,large intestine,small intestine,uterus,exterior,chest and diaphragm.There was no significant difference regarding different pathological types of CAG with different pathological elements(P<0.05),however,disease location syndrome element of the liver might be a risk factor for the development of CAG(P<0.10,OR=1.640>1);syndrome elements of disease nature was predominated by I-stagnation,Yang-deficiency,I-deficiency and dampness,also covered Yin-deficiency,blood stasis,phlegm,indigestion,heat,blood deficiency,cold and yang hyperactivity,polydipsia,damage of essence,impairment of both qi and the body fluid,blood-heat,wind,summer heat and wei-energy failed to protect the body.No evident difference was found concerning the different pathological types of CAG in the analysis of syndrome elements of disease nature(P<0.05),nevertheless,disease nature syndrome elements of Yang-deficiency,phlegm and blood stasis correlate with the pathological progress of CAG(all P<0.1,OR=1.640,1.581 and 1.608>1,respectively).3.Anxiety and depression correlate with the level increase of location syndrome element of the liver and disease nature syndrome elements phlegm(all P<0.1,OR=218.55,54.98,1.943 and 2.702>1,respectively).Conclusion:1.The level increased of location syndrome element of the liver and disease nature syndr ome elements phlegm cause by the level increase of anxiety and depression,and make the pat hological progress of CAG aggravating.2.Clinical treatment of CAG patients with anxiety and depression need to focus on the tr eatment of conditioning the liver and reducing the phlegm.