The Observation Of The Curative Effect Of Huisheng Oral Liquid Combined With Radiotherapy And Chemotherapy In The Treatment Of Locally Advanced NSCLC

Objective: refined to Huisheng oral liquid by a variety of traditional Chinese medicine components with multiple effect,less side effects,drug clinically used as an aid in the treatment of comprehensive treatment of tumor,retrogradation oral liquid is contained in promoting blood circulation to remove blood stasis,can improve the patients’ blood coagulation state,improve the flow of blood to the tumor tissue,enhance the curative effect of radiation and chemotherapy.Otherwise the literature reported that anabiosis oral liquid can improve the patients quality of life,also reduce the radiation and chemotherapy toxicity [1-2],on this basis,this test will discuss anabiosis the curative effect of oral liquid with chemoradiation therapy with locally advanced NSCLC.Methods: screening between December 2014 and February 2016 in our department treatment of locally advanced NSCLC patients,68 cases without surgical indications,by bronchoscopy mirror,fall off lung wear or pleural effusion cytology,cytology or pathological diagnosis,and confirmed for the first time.Divided into two groups by random method,including the control group,34 cases(20 male and female 14 cases;13 cases of adenocarcinoma,squamous carcinoma(21 cases.Experimental group 34 cases,18 were male,female 16 cases;15 cases of adenocarcinoma,squamous carcinoma(19 cases).Experimental group patients give chemoradiation and Huisheng oral liquid,Huisheng oral liquid by chengdu tianfu mondial group pharmaceutical co.,LTD.For production.Drug specifications and properties: brown liquid.Smell,taste bitter,bitter,10 ml/teams.Huishengoral liquid,since the radiation using 10 m L/time,3 times/d,continued until the end of radiotherapy.While the control group pure lines of radiation and chemotherapy.Radiotherapy using 6 MV-X three-dimensional conformal radiotherapy,2 gy/times,five times a week.Total 60 ~ 70 Gy.All USES include platinum chemotherapy of first-line chemotherapy scheme,and according to the patient’s general condition and clinical practice,choose the GP(cisplatin plus gemcitabine),PP(cisplatin + beautiful song)culture,TP(cisplatin plus paclitaxel)[3].In strict accordance with the body surface area to dose calculation,conventional anti-nausea and acid suppression during chemotherapy,hydration and other symptomatic treatment.Adverse reaction in the process of evaluation,and treatment after the process evaluation objective curative effect.All of the patients before and after the process treatment to detect plasma prothrombin time,activated partial prothrombin time,D-dimer,fibrin(Fib).Results: the objective response rate is higher than the control group(P < 0.05);The control group before and after treatment the blood coagulation indexes level no statistical difference,the experimental group Fib levels lower than the control group after treatment(P < 0.05);Adverse reactions,incidence of acute radiation injury were higher than control group.Conclusion: the oral liquid combined chemoradiation,retrogradation can improve the coagulation function in patients with tumor in the near future curative effect,improve,reduce the incidence of radiation and chemotherapy adverse reaction,improve the patients quality of life,increase patients’ compliance in the treatment and clinical treatment plan to ensure that the quantitative finish on time.