Retrospective Analysis Of Risk Factors Of Brain Injury In Premature Infants

Objective:Though studying the risk factors of brain injury in premature infants and avoiding the occurrence of high risk factors,reduce the incidence of brain injury in premature infants,improve the prognosis of premature infants and the qualities of their lives.Methods: To study the cranial magnetic resonance imaging of neonatal inpatients with premature infants over the past three years.According to the results of the brain MRI will have abnormal performance for the group of BIPI,no abnormalities for the control group.The neonatal group was divided into simple hypoxic ischemic injury group,simple hemorrhagic injury group,and mixed injury group.Statistical analysis of clinical data,through the analysis of relevant factors,logistic regression analysis of statistical methods to screen out the risk factors associated with brain injury in premature infants,and different brain injury group risk factors.Results: 1.229 premature infants were selected as research subjects,including control group(n=144),BIPI group(n=85);among BIPI group,simple hypoxia ischemia group(n=21),simple hemorrhagic group(n=52),the two mixed group(n=12).2.By Logistic regression analysis showed that:(1).Pregnancy,premature rupture of membranes,delivery mode,BE,mechanical ventilation,hypoglycemia and neonatal infection were associated with the occurrence of brain injury in premature infants(p <0.05),which small gestational age,low BE valueas a risk factor.(2).Low BE value,hypoxia and neonatal infection were the risk factors in the simple hypoxic-ischemic group.Neonatal infection,premature rupture of membranes,and mechanical ventilation were the risk factors in the simple hemorrhagic group.The mechanical ventilation in the mixed BIPI group was the risk factor.Conclusion: 1.Brain injury in premature infants is the result of the interaction of many factors,the basis of the development of premature infants are premature development and susceptibility.2.Small gestational age,premature rupture of membranes,low BE value,mechanical ventilation,neonatal infection is a risk factor for brain injury in premature infants.