Analysis Of Early Intervention In High-risk Infants With Brain Damage

BackgroundWith the rapid development of perinatal health care and neonatal intensive medicine,the neonatal mortality is significantly decreasing.Meanwhile,the population of high-risk infants continues to expand.According to statistics,the population of high-risk infants accounts for about 60% of live birth.Because of bad factors in prenatal,neonatal and infancy period,these children have already occurred growth and development disorders or have potential risk.Because early clinical features are atypical,it is difficult to be diagnosed.Once the opportunity of early diagnosis and early intervention is missed,it would result in dysfunction and sequel of brain damage.Therefore,high-risk infants health care has become an important part of child health service.Systematic intervention and management in high-risk infants will play a significant role in reducing the incidence of mental retardation and cerebral palsy and improving child health.ObjectiveTo explore the effect of early intervention on neurobehavioral development in highrisk infants at different stages,and provide the scientific basis for management and early intervention in high risk infants.MethodWe selected 74 high-risk infants from Neonatal Intensive Care Unit of Maternity and Child Health Hospital in Puyang from March 2014 to February 2015 as subjects,and they were divided into early intervention group A and early intervention B group according to the beginning time of intervention.In group A,interventions based on neurodevelopmental therapy were initiated from 42 days to 2 months after birth,while in group B,the same interventions were initiated from 4 months.Another 30 healthy neonates were selected from the children health care section as the normal control group(C group).Different incidence of dysreflexia,dystonia and abnormal posture were compared between group A and group B of high-risk infants.Besides,difference of developmental quotient were compared in three grougs.ResultThere was no significant difference in gender ratio,parental education levels,high risk factors and other general datas.The results of variance analysis showed that developmental quotient at 6 months and 12 months were significantly higher in A group than that in group B.When we compared developmental quotient of high-risk infants with that of normal control group at 6months,we found that developmental quotient of A group were lower than that of control group except the language area quotient.While developmental quotient of B group were lower than that of control group in five areas.At the age of 12 months,there was no statistical difference of developmental quotient between A group and the control group.But group B was lower than the normal control group in the area of adaptation,gross motor,fine motor,and the difference was statistically significant.Chi square test showed that at the age of 6 months,there was no difference in the incidence of dysreflexia,dystonia,and abnormal posture between the two groups.But at 12 months,the incidence of dysreflexia,dystonia,and abnormal posture in group A was lower than which in group B,and the difference was statistically significant.ConclusionEarly intervention based on neurodevelopmental therapy from 42 days to 2 months after birth helps high-risk infants promote neurobehavioral development and developmental quotient.Different effects stem from the different intervention time.The results show that early intervention from 42 days to 2 months of high-risk infants woks well in promoting neurobehavioral development and developmental quotient.