The Analysis Of The Pathogenic Bacteria Distribution And Drug Sensitive Test For Hepatobiliary And Pancreatic Tumor Patients With Postoperative Infection

Objective:This study is to make clear the pathogenic bacteria distribution and drug resistance by retrospectively studying the result of the bacteria culture and drug sensitive test of the samples collected from hepatobiliary and pancreatic tumor patients with postoperative infection.And to provide the basis for the rational use of antibotics to control the postoperative infection.Methods: The bacteria culture and drug sensitive test result of the samples from hepatobiliary and pancreatic tumor patients with postoperative infection between January 2013 and September 2016 were retrospectively analysed.The types of the bacteria isolated were statistically analysed,and some main types of bacteria’s drug resistance results of some common used antibotics were also analysed.BD Phoenix automatic analyzer were applied to conduct the bacteria identification and drug sensitive experiment,and the results were marked with S/I/R refer to the CLSI 2016 standard.Results:1 The samples are made up with abdominal drainage fluid(93%)。2 The pathogenic bacteria distribution: from all samples collected between January 2013 and September 2016,pathogenic bacteria were detected in 124 samples,16 types of bacteria were detected and 4 types of fungus were detected,what’s more,in 13 samples both fungus and bacteria were detected.The pathogenic bacteria include G-bacteria(72samples,52.55%),G+bacteria(47samples,34.31%).Escherichia coli(13.14%),Enterobacter cloacae 13.87%,klebsiella pneumoniae 10.95%,pseudomonas aeruginosa 10.95%,Acine-tobacter baumannii 4.38% make up the majority of the G-bacteria.The enterococcus faecium,Staphylococcus aureus,Staphylococcus haemolyticus are the main G+bacteria.Candida albicans 10.95% are the most common fungus;3 The sensitive rate and the resistance rate of G-bacteria to the commonly used antibotics: most G-bacteria are bacillus which are highly sensitive to imipenem,Meropenem and amikacin,and be resistance to penicillin and cephalosporin;4 The sensitive rate and resistance rate of G+ bacteria: most G+ bacteria are coccus which are sensitive to Vancomycin,linezolid,teicoplanin,and be resistance to penicillin,quinolone antibiotics,cephalosporin;5 Fungus are sensitive to voriconazole.Conclusion:1 The postoperation infection of the hepatobiliary and pancreatic tumor patients are mostly caused by G-bacteria,and the most common bacteria are Escherichia coli,Klebsiella pneumoniae,enterobacter cloacae which are sensitive to Carbapenems and amikacin。2 G+bacteria are mainly enterococcus faecium,Staphylococcus aureus,Staphylococcus haemolyticus which are sensitive to Vancomycin,linezolid,teicoplanin。3 Candida albicans are the most common fungus and it is sensitive to voriconazole。...