Analysis For The Risk Factors During Perioperative Period Of Drainage And Blood Transfusion Volume In Patients Undergoing Open Heart Surgery With Cardiopulmonary Bypass

Objective:To analyze the risk factors during perioperative period of drainage and blood transfusion volume in patients undergoing open heart surgery with Cardiopulmonary bypass(CPB).Methods:250 patients undergoing open heart surgery with CPB from January 2014 to June 2015 were included in this study for retrospective analysis.According to the fluid volume after surgery,we divided the patients into small drainage group(218 cases)and large drainage group(32 cases).The clinical factors during perioperative period were selected to be conducted by single factor analysis and logistic regression analysis to findout the risk factors of drainage and blood transfusion volume after surgury.To analyze if there were the statistical significances between the two group including the falling percentages of platelet,plasma fibrinogen and serum albumin.Results:1.The single factor analysis indicated that the risk factors included age > 55years(P=0.040),hypertension(P=0.010),NYHA heart function classification ≥ III level(P=0.012),preoperative renal function(P=0.009),postoperative serum albumin ≤25g/L(P=0.010),whether the tranexamic acid was used preoperatively(P < 0.001),CPB duration>120min(P<0.001),aortic crossclamp time>70min(P<0.001).Logistic regression analysis indicated that the independent risk factors include postoperative serum albumin(P=0.038),whether the tranexamic acid was used preoperatively(P=0.02),CPB duration(P=0.025).2.The falling percentages of platelet,plasma fibrinogen and serum albumin in large drainage group were much bigger than in small drainage group(P=0.02).Conclusions:1.The independent risk factors of drainage and blood transfusion volumeafter surgury include postoperative serum albumin 、 whether the tranexamic acid was used preoperatively、CPB duration.2.The lost of platelet,plasma fibrinogen and serum albumin in large drainage group were much bigger than in small drainage group.