Study On Numerical Simulation And Physical Simulation Of Biomedical Magnesium Alloy

At present,cardiovascular disease has become an important public health problem in our society.It is imperative to strengthen the prevention and treatment of cardiovascular disease.In the current medical treatment,through the biomedical material of the vascular stent implanted in the vascular lesions can support the expansion of blood vessels and maintain blood flow,which is an effective solution to the important medical means of vascular disease.Therefore,by improving the performance of in vivo implant materials and the development of new medical metal materials will improve the level of treatment of metal implantation equipment.Many patients can benefit from it,which will be of great significance.Biomedical magnesium alloys have many advantages,it has good biocompatibility and its elastic modulus is similar to human bone,which makes it become a popular research object in the biomedical material field.At present,the design of the ideal coronary stent is the focus of world research.Therefore,this study is to evaluate the performance of biomedical magnesium alloys under in vivo implantation conditions.On the one hand,based on the basic theory of finite element method,simulating WE43 magnesium alloy stent deformation behavior and mechanical response close to human conditions with the ANSYS Workbench platform;Based on the theory of fluid mechanics,we establish a fluid-solid coupling model to study the performance of magnesium alloy stent under human microenvironment;By establishing a fatigue life analysis system for biomedical magnesium alloys through n Code Design Life Fatigue Life analysis software to evaluate the fatigue life of magnesium alloys as in vivo implants.On the other hand,in order to make up the deficiency of the static immersion test on the corrosion resistance of magnesium-based implants,a biodegradable test device of biomedical magnesium alloy with resistive pump as the main component was established,and the degradation behavior of magnesium alloy was simulated And assessment.Through the numerical simulation analysis of biomedical magnesium alloy,we found that the stress concentration is easy to occur in the arc of the magnesium alloy stents.Combining with fatigue life study found that this site is prone to damage and crack propagation.In the coupling analysis,combining with WE43 alloy deformation behavior in the human body environment found that magnesium alloy stent deformation is uneven,which will hinder the flow of blood.These areas may even cause blood retention,leading to intimal hyperplasia and in-stent restenosis.Through the establishment of biomedical magnesium alloy in vitro degradation test device found that the dynamic environment has a significant effect on the degradation of magnesium alloy,the corrosion rate of the magnesium alloy in the device is faster than that the static immersion test,the gap is also growing with the growth of time.