The Relationship Between Retinal Changes And Ischemic Stroke

Stroke is the third most common cause of death in the developed world after ischemic heart disease and combined cancers,and the most common cause of serious acquired adult physical disability。However,because of the difficulty for intracranial vascular check,our research results of stroke is not enough.So,we can’t even clearly explain the pathogenesis of stroke,and this is inconsistent with its high morbidity and high mortality rate.then,the apparence of recent techniques,such as,transcranial Doppler ultrasound,positron emission tomography(PET),magnetic resonance ect.provided invaluable tools in advancing our understanding of cerebrovascular pathophysiology.However,these techniques are often expensive and available only in specialized centres,and therefore are not suitable candidates for more widespread screening of patients at risk of cerebrovascular disease.A simpler,more accessible technique is required.And retinal digital image analysis may indirectly provide such a technique.Owing to the homology between the retinal and cerebral microvasculatures,changes in the retinal vasculature may reflect similar changes in the cerebral vasculature.The potential for using the retinalvasculature as a marker of the state of the cerebrovasculature offers clear advantages,owing to the ease with which the retinal vasculature can be directly visualized in vivo,and also photographed because of its essential two-dimensional nature.