Clinical Observation Of Restoring Normal Coordination Between Heart And Kidney In The Treatment For Disharmony Between Heart And Kidney Of Insomnia

Objective: Based on clinical observation on the clinical therapeutic effects of restoring normal coordination between heart and kidney by the self-prepared prescription of Professor Zhao Jianjun for insomnia,the paper is a clinical comparison study of two insomnia therapeutic methods.The paper is to evaluate outcomes of insomnia treatment and to optimize insomnia treatment.Method: A total of 72 cases,who visited the outpatient encephalopathy department of Hospital of Changchun University of Chinese Medicine from January 2016 to December 2016,were enrolled.With respect to syndrome differentiation of traditional Chinese medicine,all cases were clinically diagnosed as “disharmony between heart and kidney”.The 72 cases were randomly divided into the treatment group and the control group.The self-prepared prescription of Professor Zhao Jianjun,oral TCM Formula Granule,was administered in the treatment group,The dosage was 150 ml,2 times per day(morning and evening after a meal,warm taking),while oral WULING capsule(Jolly Pharmaceutical;Batch No.: Z19990048)treatment was administered in the control group,The dosage was 4 capsules each time,3times per day oral(after meal).The therapeutic courses lasted for 4 weeks in both groups.After 4-week treatment,therapeutic effect were observed in both groups,while changes of symptoms were compare in patients with functional constipation before and after treatment.Result: It was indicated that the self-prepared prescription of Professor Zhao Jianjun obviously improved Pittsburgh Sleep Quality Index(PSQI)and TCM syndrome performance in patients with insomnia(disharmony between heart and kidney),and there was no adverse effect.With respect to therapeutic effect for insomnia,the efficiency rate in the group of the self-prepared prescription of Professor Zhao Jianjun was 80.56% and the total response rate was 97.20%;in the control group received WULING capsule treatment,the efficiency rate was 55.56% and the total response rate was 83.33%.The difference between the two groups was significant(P<0.05),and the before-treatment and after-treatment conditions were significantly different(P<0.05).Conclusion: The self-prepared prescription of Professor Zhao Jianjun is superior to WULING capsule treatment in improving PSQI and TCM syndrome performance of insomnia(disharmony between heart and kidney)patients.During the study period,no adverse reaction was observed in patients treated with the prescription.