The Diagnostic Value Of Ultrasonography,Contranst-enhanced Ultrasonography And X-ray Mammography In Patients With Early-stage Breast Cancer

Objectives:To investigate the diagnostic value of ultrasonography,contrast-enhanced ultrasonography and X-ray mammography in early-stage breast cancer.Methods:The clinical and imaging data of 156 patients with breast cancer and 260 patients with benign tumor of breast who underwent ultrasonography,contrast enhanced ultrasonography as well as X-ray mammography were retrospectively analyzed.The respective and combined diagnostic rates of ultrasonography,contrast-enhanced ultrasonography and X-ray mammography were evaluated and differences among them were discussed.Results:The sensitivity,specificity,false positive rate,false negative rate and coincidence rate respectively were 86.55%,58.25%,41.75%,13.45%and 68.62%for ultrasonography in 103 early-stage breast cancer patients.While,the sensitivity,specificity,false positive rate,false negative rate and coincidence rate respectively were 93.10%,70.73%,29.27%,6.89%and 77.90%for contrast-enhanced ultrasonography in 54 patients with early-stage breast cancer.For 96 patients who underwent X-ray mammography,the sensitivity,specificity,false positive rate,false negative rate and coincidence rate respectively were 64.00%,66.32%,33.67%,36.00%and 65.32%.The combined diagnosis with ultrasonography,contrast-enhanced ultrasonography and X-ray mammography showed sensitivity,specificity,false positive rate,false negative rate and coincidence rate respectively with 92.30%,98.40%,1.58%,7.69%,and 96.62%.The diagnostic accuracy rate is higher in contrast-enhance ultrasonography alone than ultrasonography and X-ray mammography alone(P<0.05).The combined diagnostic rate was higher than single use of ultrasonography,contrast-enhanced ultrasonography and X-ray mammography.Conclusion:Contrast-enhanced ultrasonography showed higher diagnostic rate in patients with early-stage breast cancer than ultrasonography and X-ray mammography.Combined diagnosis improved the diagnostic rate in patients with early-stage breast cancer,thus,play a crucial role in early diagnosis and treatment of early-stage breast cancer.