The Effect Of Visceral Fat Mass On Postoperative After Pancreaticoduodenectomy

Background:Obesity is associated with perioperative complications and has been considered a risk factor for surgical outcomes of patients undergoing abdominal surgery.The aim of this study is to evaluate the impact of the amount of visceral fat on postoperative morbidity of patients who underwent pancreaticoduodenectomy(PD).Methods:We reviewed 139 patients who underwent surgery for periampullary lesions at the First Affiliated Hospital Of Xinjiang Medical University between June 2015 and June2017.The visceral fat area(VFA)and subcutaneous fat area were calculated by computed tomography software.Results:The mean body mass index(BMI)was 23.4 kg/m~2(±3.1 kg/m~2),and the mean VFA was 99.2 cm~2(±49.5 cm~2).The incidence of clinically relevant pancreatic fistula(grade B/C)was significantly higher in the high-VFA group(≥100 cm~2).In univariate analysis,the incidence of clinically relevant pancreatic fistula(grade B/C)was significantly higher in the high-VFA group(≥100 cm~2).In multivariate analysis,the high-VFA group(≥100 cm~2)was identified as independent factors for clinically relevant pancreatic fistula.Conclusion:VFA is a better indicator for the development of pancreatic fistula after PD than BMI.High VFA(≥100 cm~2)is a risk factor for developing a pancreatic fistula after PD.