Preparation And Application Of Mxene Nanocomposite Chemically Modified Electrode

Chemically modified electrode?CME?has been applied widely in electro-catalysis,selective permeation and electrochemical sensor.Two-dimensional nanomaterials have been applied in various fields due to their large catalytic surface area,higher electron transfer rate and good optical properties,which are particularly suitable for studying electrochemical biosensors as modified material of CMEs.There are many materials like graphene with layered structure and Ti₃C₂ is a kind of two-dimensional nanomaterials and it has been applied in fields of energy storage and catalysis.However,there is little research on the composites ofTi₃C₂.In this work,some different biosensors based on composite nanomaterials of Ti₃C₂ are fabricated.These results are presented as follows:First,AuNPs@Ti₃C₂/GC sensor is prepared by electrochemical deposition.The results of dopamine detection carried by DPV with AuNPs@Ti₃C₂/GC electrode are compared with those with AuNPs/GC electrode.It is showed that electrochemical activity of modified electrode of AuNPs@Ti₃C₂/GC is apparently higher than pure gold nanoparticle electrode.The linearity range of AuNPs@Ti₃C₂/GC sensor is 0.2?200 ?M with good linear relationship between currents and concentrations and the sensor has good repeatability and stability as well.AuNPs@Ti₃C₂/GC sensor can also be used to detect dopamine in the presence of interfering substances and the recovery rate of dopamine is determined.The result shows that the AuNPs@Ti₃C₂/GC electr,ode can be applied to the detection of dopamine.Second,the electrochemical behaviors of glucose on the NiNPs@Ti₃C₂/GC electrode are studied.The current-time curve is used to quantitatively detect glucose and the detection potential is 0.5 V?vs.SCE?.The results reveals that current response is linearly correlated with glucose concentration in the range of 2 ?M-4.2 mM with low detection limit of 0.34 ?M?S/N =3?,and its stability and recovery of samples are satisfactory by compared with the published reports.The third section,the ZnO-Ti₃C₂ composite nanomaterial is prepared by direct mixing method.Meanwhile,the ZnO@Ti₃C₂/GC modified electrode is constructed and the electrochemical experiments of PZA drug are researched.The ratios between Ti₃C₂ and ZnO are investigated in the preparation of composite materials.In addition,the effects of pH and sweep rates of differential pulse voltammetry are also studied.The results of pyrazinamide detection by differential pulse voltammetry show that the introduction of ZnO improves the electrochemical performances of the sensor and promote the reduction reaction of pyrazinamide with good precision and stability.In this case,the detection range is 2.0?600 ?M.Consequently,the ZnO@Ti₃C₂/GC modified electrode is expected to be applied to the analysis of real samples.