Preparation And Properties Of Zwitterionic Shape Memory Polyurethane Based On Methyldiethanolamine

Shape memory polyurethane has been used as an important biomedical material because of its excellent physical and chemical properties.However,its application in medical field is limited due to its poor biocompatibility.Thus,adding biocompatibility in addition to shape memory functionality is quite necessary.In recent years,zwitterionic polyurethane has been paid more and more attention because of its good biocompatibility and simple preparation process.Therefore,this paper designs the MDEA-based shape memory polyurethane system,and improves the biocompatibility and shape memory performance of shape memory polyurethane by amphoteric ionization and modification.The firstly,MDEAPU series samples with HDI-MDEA as soft segment and HDI-BDO as hard segment were prepared by solution polymerization.The structure of the MDEA-based SMPUs is investigated using FT-IR,NMR.The thermodynamics and crystallinity are investigated using DSC,TGA,DMA,POM,AFM.It is found that the sample with the hard content less than 20wt% is amorphous and the sample with more than 30wt% of the hard segment will form a semi-crystalline hard phase.Additionally,the study find that all MDEA-based polyurethanes show two-phase separation structures composed of soft and hard phases,which configuration satisfies the basic structural requirements of SMP.This morphology exhibits good thermally induced SMEs with 100% shape fixity and more than 80% shape recovery.This work provides a new strategy for designing multifunctional shape memory polymers with amine-containing polyurethanes.The secondly,a series of SMPU-PS samples was synthesized using HDI,PEG6000,MDEA,1,3-PS.The structure of the SMPU-PS is investigated using FT-IR,NMR,XPS.The thermodynamics and crystallinity are investigated using DSC,TGA,DMA,POM,AFM.The thermal stability and thermomechanical properties are investigated using DMA,TGA,microcomputer universal testing machine.It is found that the shape memory performance are improved as sulfobetaine increases in the sample.The shape fixation rate and the recovery rate decrease as sulfobetaine increases when the content is too high in the sample.The study found that the series of samples of good biocompatibility using fluorescence inverted microscope,microplate reader,SEM.The study of the structure and properties of SMPU-PS-JL series samples which were successfully prepared by KH560 modified SMPU-PS series samples.The structure of the SMPU-PS-JL is investigated using FT-IR.The thermodynamics and crystallinity are investigated using DSC,TGA,DMA,POM,AFM.The thermal stability and thermomechanical properties are investigated using DMA,TGA,microcomputer universal testing machine.It was found that the SMPU-PS-JL series samples showed a higher maximum tensile stress and a lower elongation a break than the SMPU-PS series.The results show that the thermal memory properties of SMPU-PS-JL series are improved and then decreased.The study found that SMPU-0.2PS-JL,SMPU-0.8PS-JL and SMPU-1PS-JL have good biocompatibility using fluorescence inverted microscope,microplate reader,SEM.In particular,SMPU-0.8PS-JL has good biocompatibility and the shape recovery rate of 87%,which is the best performance of the sample.