The Application Of Remifentanil Target-controlled Infusion In Painless Gastroscopy In Obese Patients

ObjectiveTo explor the safety and the effect of target-controlled infusion of remifentanil on obese patients undergoing painless gastroscopy.Methods100 patients undergoing painless gastroscopy were randomly and equally allocated into 2 groups(50 each).In group R,anesthesia was induced with TCI(target-controlled infusion)of remifentanil,and the target plasma concentration(Cp)of remifentanil was set at 2ng/ml.In group N,the same volume of saline was continues infusion.MAP,RR and HR were monitored and recorded before the examination(TO),at the time point of examination start(T1),gastroscopy go through glottis(T2),the end of the operation(T3)and 5 min after examination(T4).The effect of sedation was evaluated by Ramsay Scale.Except that,gastroscopy time,the satisfaction of patient,anesthetist and endoscopist were recorded.In addition,the complications such as apnea,bradycardia,hypoxemia,myoclonus,body movement and hypotension were also recorded.Results Compared with those in group N,HR,MAP and rate of body movement were significantly decreased in group R(P<0.05).Except that,the satisfaction of patient and endoscopist were increased(P<0.05).ConclusionTCI of remifentanil can provide satisfaction sedation for obese patients undergoing painless gastroscopy with few adverse effects.