Electrochemical Degradation Of Cephalosporins In Water By Ti Based Metal Oxide Electrode

In most of the rivers in China,the existence of antibiotics is detected.With the emergence of super bacteria,drug resistance has potential threat and harm to human body.The degradation of cefepime in water by electrochemical is studied in this paper.Titanium nanotube electrode was prepared by anodic oxidation.Copper was plated on Ti nanotube electrode by cathodic reduction and calcined to form Cu @Ti nanotube electrode.The micro surface structure and electrochemical characterization of the electrode were carried out.It is deduced that the copper on the surface of the copper coated titanium nanotube electrode exists in the form of Cu20 and CuO,and the expression is CuO@Cu2O-TNTs.The electrode has good conductivity and low voltage,and the degradation rate of 15 min under low current density(25 u A/cm2)can reach more than 90%.The degradation efficiency under different operating conditions was analyzed.The results showed that the influence of the pH value of the cephalosporin on CuO@Cu2O-TNTs electrode was important,and the alkaline condition was beneficial to the degradation of cefepime.The reaction kinetics under different current density,ionic strength and initial concentration accords with first-order kinetic model.According to the fluorescence spectrum test,it was shown that · OH was produced during the electrochemical process.In combination with the result of liquid chromatography,the degradation step was the hydrolysis of large molecules first,and then.·OH attacked the beta lactam ring of cefepime to produce organic acids and aromatic substances.·OH further mineralized it into water and carbon dioxide,sulfur and nitrogen compounds.