Risk Factors Analysis For Prosthetic Joint Infections After Primary Hip And Knee Arthroplasty

OBJECTIVE To investigate risk factors for prosthetic joint infections after primary hip and knee arthroplasty,and to provide the basis for prevention form prosthetic joint infections in the early stage.METHODS Retrospective analysis the clinical information of the 28 patients who underwent the primary hip and knee arthroplasty from Mar-2013 to Mar.2016 and were suffered from_postoperative p.rosthetic joint infections,including 13 hip(11 THA,2 hemiarthroplasty of hip)and 15 knee(1 bilateral TKA)arthroplasty,were assigned as the case group;according to a 1:2 ratio,in the same period 56 patients without prosthetic joint infections were chosen as control group,then the data analysis was compared between the two groups,SPSS 17.0 software was applied to statistical analysis.The count digit of the two group were expressed by mean ± standard deviation and compared by t-tests,and the count data of the two group were on show as a percentage and compared by chi-square tests.The single factor treat as independent variable with significance was subordinated to the logistic regression analysis for multivariate analysis.RESULTS Totally 10 plants of pathogen were detected in patients with periprosthetic infections,the maximum number of pathogen is gram-positive bacteria,the major ratio in patients who underwent hip arthroplasty caused by the staphylococcus epidermidis was 38.4%,and the patients with knee periprosthetic infections aroused by the staphylococcus aureus accounted for 37.3%.The univariate analysis revealed that BMI,operation time,volume of drainage,hospital stays,past-operation history of incision,long-term use of steroids or immunosuppressor,preoperative hypoalbuminemia,asymptomatic bacteriuria,superficial infection were risk factors for prosthetic joint infections after primary hip and knee arthroplasty(P<0.05).The multivariate logistic regression analysis displayed that advanced BMI,long operation time,bigger volume of drainage,long hospital stays,past-operation history of incision,long-term use of steroids or immunosuppressor,preoperative hypoalbuminemia,asymptomatic bacteriuria,superficial infection were independent risk factors for prosthetic joint infections((P<0.05).Conclusions The consequences suggest that pathogens of prosthetic joint infections after primary arthroplasty are mainly gram-positive bacteria,advanced BMI,long operation time,bigger volume of drainage,long hospital stays,past-operation history of incision,long-term use of steroids or immunosuppressor,preoperative hypoalbuminemia,asymptomatic bacteriuria,superficial infection are remarkably inclined to increase the incidence of periprosthetic infections.