Analysis Of Clinical Correlative Factors Of Myocardial Bridging

Objectives:This paper aimed to discuss the detection rate of myocardial bridging,the risk factors and the medication situation of the patients with isolated myocardial bridge,and the related risk factors and treatment of the patients with atherosclerotic myocardial bridging by analyzing the general data and clinical data of the patients with myocardial bridging in the First Affiliated Hospital of Kunming Medical University.Methods:A retrospective analysis of 100 cases of 2713 patients who underwent coronary angiography in chronological order and complete case data in the Department of Cardiology of the First Affiliated Hospital of Kunming Medical University from December 1,2016 to December 31,2017.The patient’s general data,laboratory data,ECG data and coronary angiography data were collected in detail;they were divided into three groups:isolated myocardial bridging group,atherosclerotic myocardial bridging group and normal coronary angiography group.Baseline data,chi-square test,and Logistic regression analysis were used to compare the risk factors of isolated myocardial bridging group and normal coronary angiography group;also in the isolated myocardial bridging group and the atherosclerosis myocardial bridging group,the baseline data,chi-square test,and Logistic regression analysis were used to analyze the risk factors related to atherosclerosis myocardial bridging.Results:1.From 2713 patients with coronary angiography,75 cases of patients with myocardial bridging were retrieved,including 55 cases of male,average age was(54.2±12.5)years,20 cases of female,average age was(59.9±11.8)years.According to the exclusion criteria,after removal of 10 patients with myocardial bridging,31 patients with isolated myocardial bridging,average age(50.0±10.1)years old,including 23 males and 8 females,34 patients with atherosclerotic myocardial bridging,average age(59.2±10.9)years old,including 27 males and 9 females.According to the exclusion criteria,35 were normal coronary angiograms,and the average age was(58.3± 10.7)years,including 16 males and 19 females.2.The proportion of myocardial bridging in the left coronary artery is 92%,the right coronary artery is 5%,the left circumflex branch is 3%and the median branch is 1%.3.Six of 31 patients with isolated myocardial bridging had ST-segment changes,but there was no statistical difference between ST segment changes and isolated myocardial bridging in the degree of systolic stenosis.3 patients were diagnosed with myocardial infarction and 5 patients were unstable angina;Chi-square test showed that age,sex and smoking were statistically significant;binary logistic regression analysis showed that age,smoking was statistically significant.4.In patients with atherosclerotic myocardial bridge,the ratio of coronary artery atherosclerosis in the anterior descending coronary artery was 52.9%.Chi-square test showed that age,hypertension and dyslipidemia were statistically significant Binary Logistic regression analysis showed that age and dyslipidemia was statistically significant.5.The use rate of β-blockers was 71.0%in isolated myocardial bridging,25.8%in calcium channel blockers,22.6%in combined use,and 32.3%in antiplatelet drugs.The use rate of antiplatelet drugs in patients with atherosclerosis myocardial bridging was 85.3%,beta-blockers was 70.6%,and 88.2%in lipid-lowering drugs.Conclusions:1.The total detection rate of myocardial bridge was 2.76%(75/2713),2.03%(55/2713)for males and 0.73%(20/2713)for females.Men are more commonly found in women.2.The location of the myocardial bridge is most common in the middle of the anterior descending branch,and the atherosclerotic myocardial bridge is also most common in the middle of the anterior descending branch.3.The average age of patients with isolated myocardial bridge was younger,and there was no ST-segment alteration in ECG.4.The average age of patients with atherosclerotic myocardial bridging is older,and age,hypertension,and dyslipidemia may be the risk factors for atherosclerotic myocardial bridging.5.For patients with isolated myocardial bridges with chest tightness and chest pain,the proportion of patients without P-blockers or calcium channel blockers is high;those with atherosclerotic myocardial bridges are still not fully compliant with secondary prevention and treatment of coronary heart disease.