Evaluating Hepatic Function Of Hepatic Alveolar Echinococcosis With Magnetic Resonance Diffusion Weighted Imaging:Initial Study

Objective:To evaluate the value of Diffusion weighted imaging(DWI)and Apparent diffusion coefficient(ADC)for evaluating hepatic function of Hepatic Alveolar Echinococcosis(HAE).Methods:Retrospective analysis ADC value and DWI imaging of 68 patients and 30 cases of normal people,who underwent routine liver MRI and DWI(b value were 0 and 600s/mm~2).The 68 cases of HAE patients were divided into 3 groups according to Child-Pugh classification criteria,A group has45 cases,B group has 19 and C group has 4,The ADC value of the adjacent hepatic perenchyma was measured and standardized it with the ADC value of the cerebrospinal fulid at the same spinal cord level,that was ADC ratio=ADC/ADC spinal canal.First,the correlation between ADC ratio and Child-Pugh score was analyzed.Second,for the control group and case group what were used an independent-samples T test,while for the each case group what were used ANOVA.Results:The control group ADC ratio was 0.29±0.028,while the case group ADC ratio was 0.26±0.045,respectively,for the more,the ADC ratio of group A was0.27±0.044,the ADC ratio of group B was 0.24±0.039 and the group C was 0.21±0.026.The statistical results showed the ADC value of the case group was moderately correlated with the Child-Pugh score,r=0.432(P<0.01).The control group and case group had significant difference(P<0.01),the ADC ratio of the group A,group B and group C also had significant difference(P<0.01),but there was no difference between group B and group C(P>0.05).CONCLUSION:ADC value could be indication for evaluating hepatic function for those patients with HAE.With the hepatic function decreasing,the ADC value also decreased.