The Effect Of Transcutaneous Electrical Acupoint Stimulation On Postoperative Cognitive Function In Patients Undergoing Radical Thoracoscopic Lung Cancer Operation

Objective:To evaluate the effects of transcutaneous electrical acupoint stimulation（TEAS）on the postoperative cognitive function in patients undergoing radical resection of pulmonary carcinoma performed via video-assisted thoracoscope.Methods:A total of 67 patients scheduled for radical resection of pulmonary carcinoma under general anaesthesia at Shengjing Hospital of China Medical University were included in this study.These patients were randomly divided into 2groups using a random number table:transcutaneous electrical acupiont stimulation group（E group,n=35）and control group（N group,n=32）.30 mins prior to the induction of anesthesia,patients in E group were given transcutaneous electrical acupiont stimulation on Neiguan and Zusanli,which continued to the end of the surgery,patients in N group received no stimulation.At the timepoints of pre-operation（T₀）,after operation（T₁）,24 hours after operation（T₃）the serum concentrations of neuron-specific enolase（NSE）,S-100βwere recorded.The MMSE scores were also recorded on the first day before operation,first day and third day after operation.The incidence of POCD was also recorded and analyzed.Results:Compared with group N,the serum concentrations of NSE and S-100β,as well as the incidence rate of POCD in group E were significantly lower（P<0.05）.Conclusion:TEAS can reduce the serum concentrations of NSE and S-100βand improve cognitive function in patients undergoing radical resection of pulmonary carcinoma performed via video-assisted thoracoscope.