The Value Of Radionuclide Bone Imaging And MRI In Locating Responsible Vertebrae After Osteoporotic Vertebral Compressive Fractures

Background:Aging population in China has resulted in ever-increasing risk of OVCF.The severe pain it causes can lower the life quality of patients.Previous studies have shown that PKP has great effect in treating vertebral pain caused by OVCF.Accurately locating responsible vertebrae ensures the efficacy of PKP.MRI has been now recognized as the most effective way to locate responsible vertebrae.However,a few OVCF patients have contraindications for undergoing MRI.An alternative examination needs to be found.Objective:To compare the effect of radionuclide bone imaging and MRI in locating responsible vertebrae after OVCF.Methods:A retrospective analysis was made on 25 patients with OVCF treated by PKP from May 2015 to December 2015.There were 4 males and 21 females,at age range of 63～87 years[(73.34±6.16)years].The fractured vertebrae included 2 T4,3 T5,2 T6,2 T7,5 T8,3 T9,3 T10,7T11,9 T12,11 L1,10 L2,2 L3,5 L4 and 1 L5.Routine imaging examinations(X-ray,bone mineral density,MRI,radionuclide bone imaging)were performed on admission.ODI and VAS were estimated before operation and 1d after operation.Result of MRI and radionuclide bone imaging were compared.Results:A total of 64 vertebrae were included in our study.36 vertebrae were recognized as fresh OVCFs by MRI,and 40 by radionuclide bone imaging.Kappa-test indicated the results of the examination methods were statistically significant(P<0.05),Specificity(96.6%)and accuracy(98.4%)of MRI were higher than radionuclide bone imaging(82.8%,92.2%).Conclusions:Radionuclide bone imaging has a high consistency with MRI in locating responsible vertebrae after OVCF,but MRI is associated with higher specificity and accuracy.In exceptional cases,radionuclide bone imaging can partly replace MRI as a way to locate OVCF.