Analysis Of Etiology And Antibiotic Susceptibility Of Severe Hospital Acquired Pneumonia In Diabetic And Non-diabetic Patients

Objective:Patients with severe pneumonia often deteriorate rapidly and have a high mortality rate.Diabetics are more susceptible to infection than non diabetics because of metabolic disorders and lower immunity to the body,and patients with diabetes are the most susceptible to pulmonary infection.Susceptible bacteria in patients with basic diseases are often different from those without basic diseases,This paper studies the susceptible bacteria of patients with severe hospital acquired pneumonia to provide reference for the use of preclinical empiric drug.Methods:A total of 112 patients with severe hospital acquired pneumonia admitted to our hospital from January 2012 to December 2017 were selected as the study subjects,and their case data were retrospectively analyzed.There were 54 patients(group A)in diabetic group and 58 patients(group B)in non-diabetic group.Results:There are 39 cases of qualified sputum specimens in Group A,There are 41cases of qualified sputum specimens in Group B,The main pathogenic bacteria in the two groups were Gram-negative bacteria.The incidence of mixed infection in group A was 16.67%,and the incidence of mixed infection in group B was 13.79%.There were15 fungi in group A and 5 fungi in group B,The two groups of infected fungi were mainly Candida albicans(7 in group A and 3 in group B),The proportions of fungi in groups A and B were different,and there was statistical significance(X~2=4.34,P<0.05).Resistance rate of acinetobacter baumannii in both groups are high,Acinetobacter baumannii is more sensitive to amikacin and tigecycline.Conclusion:Gram-negative bacteria were the main pathogens in diabetic patients and non-diabetic patients with severe hospital acquired pneumonia,followed by fungi and Gram-positive bacteria.However,the proportions of the two groups of fungi differed with statistically significant.To understand the distribution of pathogenic bacteria and drug resistance in our hospital is conducive to the early selection(no pathogen test results)of suitable antibiotics in patients with severe pneumonia.