The Changes Of Retinal Vessel Diameter In The Branch Retinal Vein Occlusion And The Association With TCM Syndrome

Objective:Research the Changes of retinal vessel diameter in the branch retinal vein occlusion and the association with TCM Syndrome.Method:We use the case review method and Collect the hospitalized cases who are diagnosed the branch retinal vein occlusions in Cheng Du university of Traditional Chinese Medicine hospital from January 2015 to January 2017,We bring into the 25 cases 50 eyes use the standards of this study and the 23 cases 46 eyes in the control group use the standards of this study strictly.We use the SD-OCT of Heidelberg manually measured the retinal arteriovenous internal and outer diameter of the value by the four quadrant(above the temporal,nose above,below the nose,under the temporal)of the two groups cases from the center of optic disk about 600 microns away.Separately calculated the retinal arterial values,the venous valuesand the inner and the outer diameter ratio(use VNS to denote the inner diameter ratio and use ANS to denote the outer diameter ratio),Inspect the repeatability of the measurement method.Collect the all subjects’ general condition(the gender,the age),the eye condition(which one is the ill eye,blocking vascular)at the same time and the patients with BRVO group general history(high blood pressure,dyslipidemia,coronary heart disease,arteriosclerosis,etc.),laboratory results(blood routine,blood clotting,blood rheology)and the TCM syndrome classification.Analysis the branch retinal vein occlusion(BRVO)of vascular diameter changes about the artery or the vein and Research the relationship of Traditional Chinese Medicine.Result:1.There is no statistically significant differences between the BRVO group and the control group in the gender and in the age(P>0.05),It is balanced in the two groups,They can be compared.2.In the control group,The right eyes and the left eyes are respective compared in the four quadrant(above the temporal,nose above,below the nose,under thetemporal),Their VNS and ANS are no statistically significant in the each quadrant(P>0.05).3.BRVO group’s sick eyes and the control group’s eyes are respective compared in the four quadrant(above the temporal,nose above,below the nose,under the temporal),Their VNS and ANS are statistically significant(P<0.05).4.BRVO group’s healthy eyes and the control group’s eyes are respective compared in the four quadrant(above the temporal,nose above,below the nose,under the temporal),Their VNS and ANS are statistically significant(P<0.05).5.BRVO group’s sick eyes and their healthy eyes are respective compared in the four quadrant(above the temporal,nose above,below the nose,under the temporal),The two quadrant’s VNS and ANS in the two quadrant(above the temporal and under the temporal)are statistically significant(P<0.05),the rest of the quadrant were no statistical significance.6.BRVO group’s sick eyes of blocking vascularand the healthy eyes are respective compared in the two quadrant(above the temporal,under the temporal),Their VNS and ANS are statistically significant(P<0.05).7.BRVO groups’ s sick eyes are respective compared in the four quadrant(above the temporal,nose above,below the nose,under the temporal)in the different TCM syndrome type,The qi stagnation and blood stasis group’s VNS are statistically significant(above the temporal,under the temporal)(P<0.05),the rest two syndrome types in each quadrant is no statistical significance(P>0.05),The comparison of the three syndrome types’ ANS in each quadrant is no statistical significance(P>0.05).8.There is no significant differences in VNS and AVS between the four quadrants of the healthy eyes of the BRVO group’s in the Three TCM syndromes(P>0.05).9.BRVO group’s patients’ Blood lipids,blood coagulation function,the related parameters of hemorheology examination and abnormal platelet count rate are high.Conclusion:1.The ratio of inner and outer diameters of retinal vessels are smaller in theBRVO patients than who are not BRVO,They are more significant of the local changes of retinal vessels in the BRVO patients than who are not BRVO.The ratio of the inner and outer diameters of the temporal vessels in the diseased eyes of BRVO are smaller than the healthy eyes of BRVO,They are more significant of the local changes of the temporal vessels in the diseased eyes of BRVO than the healthy eyes of BRVO.So the quantitative analysis of retinal vessels can be used as an important index to observe BRVO retinal microvascular changes.2.The ratio of inner and outer diameters of retinal vessels are smaller in the temporal lobe in the stagnation of Qi and blood stasis syndrome than the yin deficiency yang hyperactivity syndrome or phlegm and blood stasis syndrome of BRVO,So the changes of the retinal microvascular may be associated with TCM syndromes of BRVO.