To Compare The Value Of GRACE Score And NT-proBNP For The Prediction Of Hospital Mortality In Patients With Acute Myocardial Infarction

Objective:To compare the value of the global registered acute coronary events(GRACE)score and amino terminal brain natriuretic peptide precursor(NT-proBNP)for the prediction of hospital mortality in patients with acute myocardial infarction(AMI).Methods:240 patients with AMI were retrospective included between June 2016 and May 2017 from the first hospital of shanxi medical university.Baseline information were collected when patients were hospitalized as well as GRACE score.NT-proBNP level was measured.Incidence of mortality of patients during hospitalization was observed.Regression of multivariate logistic analysis was used to analyze correlation between hospital mortality and GRACE score or NT-proBNP level.Draw the ROC curve of hospital mortality in AMI patients predicted by combination of GRACE score and NT-proBNP.Results:1.In dead group NT-proBNP level,GRACE age,hyperlipidemia and smoking score of AMI are higher than the survival group,and the difference is statistically(p<0.05).2.AMI patients have the highest mortality rates in high risk group,and hospital mortality rates are different in three group,the difference is statistically(p<0.05).3.Mortality risks of NT-proBNP>888.5pg/mL in patients is higher than NT-proBNP<8 88.5pg/mL.4.Results of linear regression showed that GRACE score was positively associated with IgNT-proBNP level(r=0.57、P<0.001,b=0.01、P<0.001).5.Regression of multivariate logistic analysis was that GRACE score,NT-proBNP level,age,smoking and hyperlipidemia are independent risk factors of hospital mortality(P<0.05).6.Draw the ROC curve,determine and compare the AUC,AUC of GRACE score is 0.975,lgNT-proBNP is 0.940 which AUC of the former is greater than the latter,combination of two is 0.982which is the biggest square.Conclusion:1.GRACE score is correlated with NT-proBNP level in patients of AMI.2.there is predictive value of GRACE score、NT-proBNP and combination of two on mortality risk;and combination of two has a higher predictive value than GRACE score、NT-proBNP.