Research About Distribution And Dynamic Variation Of Traditional Chinese Medicine Syndrome In Perioperative Period Of Gastric Cancer

Objective(1)To cognize the TCM syndrome distribution and dynamics variation in gastric cancer.(2)Explore the application method of factor analysis in Chinese medicine syndrome,Comparison the differences between cluster analysis and factor analysis in Chinese medicine syndrome by statisticsMethods Collect the survey data of TCM syndrome in perioperative period of gastric cancer,included 20 TCM symptoms,tongue and pulse.All the 4 surveys were respectively collected on 1 day pre-operation,3 days after the operation,7 days after operation and 10 days after operation.Establish the database by inputting all the data of 155 patients into computer.First of all,analysis all the syndromes’ frequency to exclude the symptoms which frequency below 5%;Then all the left syndromes as variable were analysed by cluster analysis method and factor analysis method to classify.Invite some expert to diagnosis the syndrome combined with the tongue and the pulse,to show how it distributed.At last compare the syndrome distribution all the 4 time surveys,to show the dynamic variation.Results 17 symptoms as variable were analysed by clustering and factor analysis at pre-operation,the statistical results were divided into three categories,experts discriminated 3 types symptom,45 cases of qi and yin deficiency(29.03%),40 cases of liver and stomach unharmony(25.81%),36 cases of qi stagnation and blood stasis(23.23%),34 cases without an identified syndrome(21.93%).12 symptoms as variable were analysed by clustering and factor analysis at 3 days after the operation.the statistical results were showed the same as before,experts discriminated 4 types symptom,35 cases of qi and blood deficiency(22.58%),60 cases of qi and yin deficiency(38.71%),15 cases of qi stagnation and blood stasis(9.68%),45 cases of yin deficiency and internal heat(29.03%).14 symptoms as variable were analysed by cluster analysis and factor analysis at 7 days after operation,the results were divided into three categories,experts discriminated 3 types symptom,52 cases of qi and yin deficiency(33.55%),28 cases of qi and blood deficiency(18.06%),65 cases of heat and dampness combined(41.94%),10 cases without an identified syndrome(6.45%).9 symptoms as variable were analysed by cluster analysis and factor analysis at 10 days after operation,the results were divided into 2 categories,experts discriminated 2 types symptom,47 cases of heat and dampness combined(30.32%),46 cases of qi and yin deficiency(29.68%),62 cases without an identified syndrome(40%).Conclusion TCM syndromes of the perioperative period in gastric cancer is deficiency,including the blood deficiency,qi deficiency,yin deficiency,and accompany with heat,dampness,qi stagnation and blood stasis.Because of the tumor consumption,improper diet and emotional stimulation,the pre-operation syndromes include qi and yin deficiency,liver and stomach unharmony,qi stagnation and blood stasis.The key syndrome of 3 days after the operation is qi and blood deficiency.Because of the operation lead to qi and blood deficiency,some qi and yin deficiency maybe developed into yin deficiency and internal heat.7 days after operation,the patients get recover,yi and blood deficiency and qi and yin deficiency get reduced,with the taking food,the patients appeared indigestion,showed heat and dampness combined.10 days after operation,the patients get well recover to normal,but still have some weaken patients had qi and yin deficiency or heat and dampness combined.These two kinds of data mining technology was no significant difference,both can be used in traditional Chinese medicine syndrome research.