Correlation Between Peripheral White Blood Cells And IL-6 And C Peptide In Patients With Diabetic Retinopathy

Background: diabetic retinopathy is a common complication of diabetic patients.With the incidence of diabetes,the number of diabetic retinopathy is also on the rise.Diabetic retinopathy has a high rate of blindness.If it is not timely to intervene in the early stage of the patient’s disease,the prognosis of the patients is most unsatisfactory.At the same time,diabetic retinopathy has the characteristics of not obvious early symptoms,which makes the early diagnosis of patients very difficult.In previous clinical or basic studies,IL-6 and C peptides have been demonstrated to be more or less involved in the pathogenesis of diabetic retinopathy,but the results of this study can be directly applied to the early clinical diagnosis of diabetic retinopathy,and so far no evidence has been demonstrated.Objective: To investigate the proportion of peripheral blood leucocyte,IL-6 and C peptide in patients with diabetic retinopathy,and to determine the risk of retinopathy in diabetic patients.Methods: 25 patients with diabetic retinopathy treated in the Department of Endocrinology,the First Affiliated Hospital of Fujian Medical University,January 2012-2018 March were selected,and 25 patients with no diabetic retinopathy were selected from the Department of endocrinology in the First Affiliated Hospital of Fujian Medical University in March January 2012.The results of blood routine,IL-6,C peptide release experiments in the two groups were statistically analyzed,and then the SPSS 24 software was used for statistical analysis.When the results were expressed as P<0.05,the data difference was statistically significant.Results: the level of serum IL-6 in the experimental group was significantly higher than that in the control group.The levels of 0h C peptide and 2H C peptide in the experimental group were lower than those in the control group.The fasting blood glucose,postprandial 2H blood sugar,the total number of white blood cells,neutrophils count,lymphocyte count,and mononuclear cell count were higher in the experimental group.Conclusion: the number of leukocyte count,neutrophils count,lymphocyte count,monocyte count,0h C peptide,2h C peptide,IL-6 level,and other items in diabetic retinopathy patients with diabetic retinopathy are significantly different from those of diabetic retinopathy,and the use of this test can be used.It is effective to assess the risk of diabetic retinopathy in diabetics.