Investigation On The Prevalence And Prognostic Factors Of Respiratory Distress Syndrome For Premature Infants In A Hospital Of Qiqihar

Objective:To investigate the situation of neonatal respiratory distress syndrome(NRDS)patients and their mothers,analyzes the risk factors that may lead to the occurrence of NRDS clinically,and explores various high risk factors related to the occurrence of NRDS,so as to provide active prevention,clinical diagnosis and treatment of NRDS.To provide a scientific basis,while reducing the probability of complications,improve the prognosis of children,improve the quality of life of children,while reducing the economic burden of children’s families to save social medical resources.Methods:All live births of premature infants whose gestational age was less than 37 weeks were delivered in a hospital of Qiqihar City from January 2016 to December 2017.The general data,such as sex,gestational age,birth weight and incidence of respiratory distress syndrome,parity,multiple pregnancy,mode of delivery,maternal condition,premature rupture of membranes,and so on were collected.Perinatal factors such as placenta previa,gestational hypertension,gestational diabetes mellitus and complications such as intracranial hemorrhage,pulmonary hemorrhage,bronchopulmonary dysplasia,retinopathy of premature infants,patent ductus arteriosus and so on.A retrospective case-control study was conducted to divide all the subjects into respiratory distress syndrome group and non-respiratory distress syndrome group according to whether or not respiratory distress syndrome occurs in premature infants.The sex,gestational age,birth weight and respiratory distress of premature infants with and without respiratory distress syndrome were compared between the two groups.General information on the occurrence of syndromes,such as parity,parity,multiple pregnancy,mode of delivery,mother’s condition,premature rupture of membranes,placenta previa,pregnancy-induced hypertension,gestational diabetes mellitus andintracranial hemorrhage,pulmonary hemorrhage,bronchopulmonary dysplasia,retinopathy of premature infants,patent ductus arteriosus,etc.Ridge regression analysis was used to analyze the high risk factors of respiratory distress syndrome in hospitalized premature infants.Results:There was no significant difference in sex and age between children with and without respiratory distress syndrome(P > 0.05).The difference of the gestational age,birth weight,gestational age,births,parity,multiple births,mother’s occupation and mother’s educational background of children with respiratory distress syndrome and those without respiratory distress syndrome was statistically significant(P <0.05).There was no significant difference of sex and age of mother of the children with and without respiratory distress syndrome(P> 0.05)between the two groups.The different of amniotic fluid clearance,amniotic fluid volume,premature rupture of membranes,intrauterine distress,placenta previa,placental abruption,gestational hypertension,gestational diabetes mellitus,intracranial hemorrhage,pulmonary hemorrhage,bronchopulmonary dysplasia,patent ductus arteriosus,neonatal infection,persistent pulmonary hypertension and the use of ventilators were statistically significant(P < 0.05).Multiple collinearity existed in the strain,F=5.247,P= 0.001 by ridge regression test,suggesting that the regression model fitted well,including birth weight,parity,multiple births,mode of delivery,history of asphyxia,inhalation,umbilical cord,amniotic fluid clearance,amniotic fluid,maternal age,premature rupture of membranes,intrauterine distress,placenta previa,placental abruption,pregnancy.Pregnant hypertension,gestational diabetes mellitus,intracranial hemorrhage,pulmonary hemorrhage,bronchopulmonary dysplasia,patent ductus arteriosus,neonatal infection,persistent pulmonary hypertension,ventilator were associated with the occurrence of respiratory distress syndrome in hospitalized premature infants.Conclusion:415 premature infants in a hospital in Qiqihar City were investigated and 116 cases of respiratory distress syndrome(27.95%).It shows that the sex,gestational age,birth weight and the incidence of respiratory distress syndrome in premature infantswith and without respiratory distress syndrome,and other general information,parity,parity,multiple pregnancy,mode of delivery,maternal status,fetal age Premature rupture of membranes,placenta previa,gestational hypertension,gestational diabetes and other perinatal factors and intracranial hemorrhage,pulmonary hemorrhage,bronchopulmonary dysplasia,retinopathy of premature infants,patent ductus arteriosus complications.