| Objective: To observe the clinical efficacy of Bufei Yishen combined with lip-abdominal respiration in the treatment of chronic obstructive pulmonary disease(Lung and kidney deficiency),and to provide more clinical ideas for the treatment of chronic obstructive pulmonary disease by integrated traditional Chinese and Western medicine.Methods: Using randomized controlled trials,120 patients with moderate-severe chronic obstructive pulmonary disease(Pneumo-Kidney Qi Deficiency Syndrome)were divided into four groups: A.Control group B.Chinese medicine group C.Contractive lip-abdominal breathing group D.Comprehensive treatment group.Group A was given conventional western medicine;Group B was treated with traditional Chinese medicine(Tanchuan Guben Decoction)based on conventional western medicine;Group C was treated with routine basic upward lip-abdominal breathing exercises;Group D was treated with conventional basic western medicine.Chinese medicine and lip reduction-abdominal breathing training.Observe changes in lung function,changes in TCM syndrome scores,CAT scores,modified MRC dyspnea index(mMRC),6-minute walking distance(6MWD),BODE index change,and safety before and 6 months after admission in each group.Sex indicators,including liver and kidney function(ALT,AST,BUN,Cr),blood routine,urine routine,routine stool,and electrocardiogram.Results:(1)CAT score: Within the group,except for the control group,the scores of the other three groups all had a decrease in CAT scores(P<0.05);the comparison between the groups was better than that of the control group,the Chinese medicine group,and the lip reduction.Respiratory group,but the Chinese medicine group and the lip-abdominal breathing group were superior to the control group,Chinese medicine group and lip-abdominal breathing group had no significant difference(P> 0.05).(2)6MWD: The 6-minute walking distances of the four groups within the group were all increased,but there was no statistical significance in the control group(P>0.05).The comparison group was the best among the groups,and the lip-abdominal breathing group was superior to the Chinese medicine group.Both groups had statistical significance(P<0.05).(3)TCM Syndrome Scores: Intra-group comparison Four groups of TCM symptoms improved,but there was no statistical significance in the control group(P>0.05);among the groups,the comprehensive group was the best,the Chinese medicine group and the lip-belly type.The respiratory group followed,and the Chinese medicine group was better than the lip-abdominal breathing group.(4)mMRC: Intragroup comparison,except for the control group,the other groups were statistically significant(P<0.05);between the groups,there was no significant difference between the groups(P>0.05).(5)Pulmonary function: Within the group,FEV1 was improved.Only the comprehensive group had statistical significance(P<0.05).FEV1 in the control group decreased.FEV1 in the Chinese medicine group and lip-abdominal breathing group improved,but the difference was not significant.Statistical significance(P>0.05);between groups,the difference between the comprehensive group,the Chinese medicine group,and the lip-abdominal respiration group was statistically significant(P<0.05),but the comparison between the three groups was not significant.Statistical significance(P>0.05);There was no significant difference in the improvement of FEV1/FVC between groups and between groups(P>0.05).(6)BODE index: In the group comparison,except for the control group,the other three groups had a statistically significant BODE index(P<0.05);the comparison group was the best among the groups,followed by the Chinese medicine group and the lip-abdominal breathing group.Both were superior to the control group,but there was no significant difference between the Chinese medicine group and the lip-abdominal breathing group(P>0.05).Conclusions: 1.Bufei Yishen combined traditional Chinese medicine reduce lip-abdominal breathing training can improve pulmonary function in patients with chronic obstructive pulmonary disease(Lung and kidney deficiency),significantly improve patient endurance and quality of life,reduce the clinical symptoms and reduce Breathing difficulty grading,and significantly better than the simple Chinese medicine group and reduction lip-abdominal breathing training group.Worthy of clinical application.2.Chinese medicine Bufei Yishen treatment and lip contraction-abdominal breathing training can delay the decline of pulmonary function in patients with progressive decline,but not statistically significant(P> 0.05).And both treatment methods can improve the patient’s symptoms,improve exercise tolerance and quality of life.However,in improving clinical symptoms,Chinese medicine is better than reduced lip-abdominal breathing training;in improving exercise tolerance,reduction of lip-abdominal breathing training is better than traditional Chinese medicine treatment. |