Clinical Effect Of Huatanxiaoying Decoction On Thyroid Nodule (Qi Stagnation And Phlegm Obstruction)

Objective:In this study,the clinical efficacy and safety of huatan xiaoying decoction in the treatment of thyroid nodules(qi stagnation and phlegm-blocking type)were preliminarily evaluated by comparing the changes of TCM symptoms and the size of thyroid nodules,so as to provide new research ideas and theoretical basis for the treatment of thyroid nodules by TCM.Methods:From December 2017 to November 2018,72 patients diagnosed with thyroid nodule syndrome differentiation of traditional Chinese medicine as qi stagnation and sputum obstruction and meeting the inclusion criteria in the first department of geriatric diseases,affiliated hospital of changchun university of Chinese medicine were randomly divided into control group and treatment group,including 36 patients in the control group and 36 patients in the treatment group.Both groups were given life management,the control group was given decoction of prunella decoction,the treatment group was given huatan xiaogall decoction,the treatment course of both groups was 4weeks.The changes of treatment indexes and safety indexes were observed before and after treatment.Results:68 cases were finally completed in this study,and the baseline comparison of gender and age before treatment between the two groups showed no statistical difference(P > 0.05),which was comparable.After treatment(1)in terms of TCM syndromes,the effective rate in the treatment group was 94.11%,and that in the control group was 73.53%.The effective rate in the treatment group was significantly better than that in the control group.After treatment with huatan xiaoying decoction,the clinical symptoms(except chest tightness,discomfort and poor tolerance)of thyroid nodule patients with qi stagnation and phlegm obstruction were effectively improved(P < 0.05).(2)nodule size: there was no statistical difference between huatan xiaoying decoction group and prunella vulgaris oral liquid group(P > 0.05).(3)safety comparison: before and after the test,the blood routine,urine routine,ecg and thyroidfunction of the two groups were within the normal range,indicating that no adverse conditions occurred in the two groups,which was safe and reliable.