| Objective:This subject aims at under the guidance of the tutor professor HongMei Nan.By observing the clinical effect of yuanzhi anshen decoction on chronic insomnia(imbalance between heart-yang and kidney-yin),comparative study on the clinical treatment of insomnia.Methods: From January to November 2018,a total of 72 patients were selected from the outpatient department of encephalopathy of the affiliated hospital of Changchun university of traditional Chinese medicine.The patients were divided into control group(basic treatment + oral wuling capsule)and treatment group(basic treatment + yuanzhi anshen decoction),with 36 cases in each group.The control group was treated with basic treatment and Wuling Jiaonang.It is on this foundation that that treatment group take the yuanzhi anshen decoction.This subject is carried out for 4 weeks.Conduct follow-up observation and record data for a period of 3 months after the completion of the subject study.The indexes of Pittsburgh sleep quality index and TCM syndrome score of the patients at week 4 and 3 months later were recorded,and then the numerical statistical analysis was performed by SPSS software.Draw valid conclusions.Results:In the course of the treatment,the 72 patients were not detached during the treatment and follow-up.Before treatment,age,gender,PSQI score before treatment and TCM syndrome score in baseline data were compared,and the two groups were comparable(P > 0.05).(1)After treatment,PSQI scores of patients in both groups were changed compared with those before treatment.The comparison of self before and after two integrals was P <0.05.The difference was statistically significant.The results indicated that both the treatment group and the control group could improve the sleep quality of patients.The scores of patients in the two groups after treatment were compared with each other(P< 0.05),and the difference was statistically significant.This indicated that the drugs in the treatment group were better than those in the control group in improving sleep quality.(2)After 4 weeks of treatment,the TCM syndrome points of the patients in both groups were changed compared with those before treatment.The comparison of the two points before and after themselves P< 0.05.The difference was statistically significant.The results indicated that both the treatment group and the control group could improve the TCM syndromes of the patients.The scores of patients in the two groups after treatment were compared with each other(P< 0.05),and the difference was statistically significant.This indicated that the drugs in the treatment group were superior to those in the control group in improving TCM symptoms.(3)After 4 weeks of treatment,the total effective rate of the treatment group was91.67%.The control group was 83.33%.The difference was statistically significant(P<0.05),indicating that the therapeutic effect of the treatment group was better than that of the control group.(4)The patients were followed up for 3 months,and the TCM syndrome score and PSQI score of the patients were different from those of the patients treated for 4 weeks.The scores of the two groups were compared with the scores of the four weeks of treatment.Results: P> 0.05(no statistical significance)in the treatment group and P< 0.05(statistical significance)in the control group.Follow-up after 3 months of two integral comparison respectively,P<0.05(the difference was statistically significant).Indicate that that long-term effect of the treatment group is more stable in terms of improve the Chinese medicine syndrome and sleep quality.(5)It was found that that total effective rate of treatment group for 3 month was 86.11 percent,and the total effective rate of the control group was 77.78 percent,two groups of patients after the follow-up can be obtained after comparing the total effective rate,the difference was statistically significant(P< 0.05).Results after 3 months of follow-up,the efficacy of the treatment group was more stable.Conclusion: Yuanzhi anshen decoction in improving the total score of PSQI and the efficacy of TCM syndromes in chronic insomnia(imbalance between heart-yang and kidney-yin),Yuanzhi anshen decoction is superior to Wuling Jiaonang.The efficacy wasstable and no adverse reactions were observed after 3 months follow-up. |
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