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Relationship Between Admission Serum Potassium Level And Long-term Mortality In Patients With Acute ST-segment Elevation Myocardial Infarction Underwent Percutaneous Coronary Intervention

Posted on:2020-09-30Degree:MasterType:Thesis
Country:ChinaCandidate:H J XuFull Text:PDF
GTID:2404330572973468Subject:Internal medicine
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Objective: To investigate the relationship between admission serum potassium level and long-term mortality in patients with acute ST-segment elevation myocardial infarction underwent percutaneous coronary intervention.Methods:This was a respective analysis of 1379 patients who underwent PCI in the First Betnune Hospital of Jilin University from January 2015 to December 2015,according to the exclusion criteria,1125 patients were included in this study finally.Patients were divided into 5 groups according to admission serum potassium level(mmol/L),<3.5(120 cases),3.5-<4.0(481 cases),4.0-<4.5(417 cases),4.5-<5.0(89 cases),?5.0(18 cases),the mortality of five groups of patients after 18 months was compared.Results:1.There was a U-shaped relationship between admission serum potassium level and mortality,this relationship still existed after multivariate adjustment.2.In a multivariate Cox-proportional regression analysis,compared with 4.0-<4.5mmol/L(mortality 4.6%)group,the mortality risk was lower for serum potassium level of 3.5-<4.0mmol/L(mortality 1.7%)(HR 0.300,95% CI 0.125 to 0.791,P=0.007),the mortality risk was greater for serum potassium level of <3.5mmol/L(mortality 14.2%)(HR 2.429,95% CI 1.243 to 4.748,P=0.009)and?5.0mmol/L group(mortality 22.2%)(HR 3.090,95% CI 1.024 to 9.326,P=0.045).Conclusion: In patients with STEMI underwent PCI,there was a U-shaped relationship between admission serum potassium level and long-term mortality;the long-term mortality risk was lowest in the group of patients with admission serum potassium level of 3.5-<4.0mmol/L.The long-term mortality risk was significantly greater in the group of patients with serum potassium level of <3.5mmol/L or?5.0mol/L.
Keywords/Search Tags:Myocardial infarction, Angioplasty, transluminal,percutaneous coronary intervention, mortality, Serum potassium
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