Prevention Of Postoperative Incision Infection And Fat Liquefaction By Incision Irrigation During Open Appendicitis

ObjectiveIn patients with generalized appendicitis resection of the general surgery,after the suture of the external oblique aponeurosis,respectively,the metronidazole and iodophor irrigation incision were compared with the surgical incision without any irrigation,and the infection of each group was compared.And the incidence of fat liquefaction.To analyze the difference of postoperative incision infection rate and fat liquefaction rate,to explore the effect of intraoperative irrigation and different irrigation fluid on wound healing,and provide methods and data support for clinical prevention of wound infection and fat liquefaction in general surgery.MethodA total of 300 patients with general appendectomy underwent general surgery from July 2016 to March 2019 in the Affiliated Central Hospital of Shenyang Medical College,and were randomly divided into 3 groups.In the experimental group 1 and 2,the incision was washed with 0.5%metronidazole and 0.5%iodophor after suturing the external oblique aponeurosis.The control group was sutured without any irrigation after suturing the external oblique aponeurosis.The incidence of postoperative incision fat liquefaction and infection was observed and compared.Result1.Incision infection:no flushing group:9 cases of postoperative wound infection.Intraoperative metronidazole flushing group:1 case of postoperative wound infection.Intraoperative iodophor flushing group:2 cases of postoperative wound infection.The incision infection rate of the unwashed intraoperatively was significantly higher than that of the intraoperative metronidazole and iodophor wash group(P<0.05).The infection rate of intraoperative metronidazole flushing group was lower than that of intraoperative irrigation group using iodophor(P>0.05).2.Incision fat liquefaction:no flushing group during operation:8 cases of postoperative incision fat liquefaction.Metronidazole flushing group:1 case of postoperative fat liquefaction.Iodine flush group:postoperative fat liquefaction was 4 cases.The liquefaction rate of intraoperative infusion of metronidazole was significantly lower than that in the untreated group and the intraoperative iodophor group(P<0.05).There was no statistical analysis between intraoperative iodophor flushing and intraoperative flushing.Difference(P>0.05).Conclusions1.Intraoperative iodophor irrigation incision is effective in preventing postoperative wound infection and has no obvious effect on preventing fat liquefaction.2.Intraoperative metronidazole irrigation is effective in preventing postoperative incision infection and fat liquefaction.Metronidazole irrigation incision can significantly reduce the infection rate of postoperative incision and postoperative fat liquefaction rate,which is worthy of extensive use in open appendectomy.Promotion.