| Objective:The main objective of this study is to analyse the Changing trends and characteristics of registration rate,sputum smear positive rate,sputum culture positive rate and drug resistance rate of pulmonary tuberculosis(PTB)patients from 2011 to2017 in Jilin Province.In order to provide scientific basis for the tuberculosis control and public health administrative department to carry out the strategies and measures of tuberculosis prevention and control in Jilin Province.Methods:Collect the basic information(gender,age,nationality,occupation,type of household registration,drug fast,registration and treatment classification,etc.)and examination information(sputum smear and sputum culture,etc.)of PTB cases registered in TB Information Management System from 2011 to 2017 in Jilin Province.IBM SPSS 24.0 statistical software and Excel office software were used to date processing and analysis.Results:1.The average registration rates of total,male and female PTB patients from2011 to 2017 in Jilin Province were 55.29/100,000,76.05/100,000 and 33.91/100,000,respectively.The average registration rates of initial treatment and retreatment PTB patients were 18.05/100,000 and 2.99/100,000,respectively.The registration rate of PTB patients declined year by year from 2011 to 2016 and increased slightly in 2017.The registration rate of male patients was more than twice that of female patients in each year.2.Based on the registration rate of PTB patients in 2011,the descent velocity(41.28%)and annual decreasing rate(7.32%)of registration rate in female PTB patients were higher than that in male patients(descent velocity was 37.70% and annual decreasing rate was 6.54%.)during the seven years.And the descent velocity(56.58%)and annual decreasing rate(11.24%)of registration rate in retreatment patients were higher than that in initial treatment patients(descent velocity wasIV37.48% and annual decreasing rate was 6.49%).3.Among the 106,350 cases of PTB patients,sputum smears were examined in105,408 cases(99.1%),and 39,793 cases(37.8%)of which were smear positive.There were statistically significant differences in the smear positive rates of PTB patients among different years,regions,ages,gender,nationalities,occupations and household registration types(P<0.001).With the increase of year,the smear positive rate of PTB patientst was on the decline.The smear positive rates were higher in Siping(47.9%)and 45~59-year-old group(42.6%).The smear positive rate of PTB patients in males(39.7%)was higher than that in females(33.3%).The smear positive rate of PTB patients in Korea nationality(41.3%)was higher than that in Han nationality(37.6%).The smear positive rate was higher in the PTB patients whose occupation was farmer / herdsman / fisherman(40.1%)and lower in the PTB patients of kindergarten children / scattered children / students(17.2%).The smear positive rate of PTB patients in non-floating population(38.1%)is higher than that in floating population(20.2%).4.Sputum culture was examined in 9,363 patients(8.8%)with PTB,and 4,006cases(42.8%)of which were culture positive.There were statistically significant differences in the culture positive rates of PTB patients among different years,regions,ages,gender,nationalities,occupations(P<0.001).The culture positive rates were higher in 2011(100.0%)and 2012(96.9%).The culture positive rates were higher in Yanbian(100.0%)and 30~44-year-old group(96.9%).The culture positive rate of PTB patients in males(44.7%)was higher than that in females(38.1%).The culture positive rate of PTB patients in Korea nationality(53.6%)was higher than that in Han nationality(42.0%).The culture positive rate was higher in the PTB patients whose occupation was workers/migrant workers(47.3%)and lower in the PTB patients of kindergarten children / scattered children / students(31.2%).5.The smear positive rate and culture positive rate of retreatment patients were higher than that of initial treatment patients(P<0.001).The smear positive rates increased first and then decreased with age in male initial treatment patients,male and female retreatment patients.The smear positive rate of female initial treatment patients tend to be on the rise with age.6.Among the 40,663(38.2%)PTB patients with positive tubercule bacillus,4280cases(10.5%)were screened for drug resistance,and 1,096 cases(25.6%)of which were drug resistance.There were statistically significant differences in the drugresistance rates of positive tubercule bacillus patients among different years,regions,gender and the type of treatment(P<0.001).Drug resistance rate of bacterium-positive PTB patients declined gradually from 2013.The drug resistance rate was higher in Changchun(48.0%).The drug resistance rate of bacterium-positive PTB patients in males(27.2%)was higher than that in females(20.9%).The drug resistance rate of retreatment PTB patients with bacterium-positive(39.5%)was higher than that of initial treatment patients(20.5%).Drug resistance rate declined gradually with age in PTB patients with bacterium-positive(P<0.001).Conclusion:1.From 2011 to 2016,the registration rate of PTB patients in Jilin Province showed a downtrend with the years grow.The average registration rate was55.29/100,000,which was lower than the national average.The registration rate of male patients was more than twice that of female patients.2.The descent velocity and annual decreasing rate of registration rate in female PTB patients were higher than that in male patients.The descent velocity and annual decreasing rate of registration rate in retreatment PTB patients were higher than that in initial treatment patients.3.The overall smear positive rate of PTB patients in Jilin Province is higher,but the smear positive rate of PTB patients was on the decline with the increase of year.The smear positive rates were higher in 45~59-year-old group,male.Korea nationality and farmer / herdsman / fisherman PTB patients.4.The smear positive rate and culture positive rate of retreatment patients were higher than that of initial treatment patients.5.The drug resistance rate of bacterium-positive PTB patients in Jilin province is higher.The drug resistance rate of bacterium-positive PTB patients in males was higher than that in females,the drug resistance rates of retreatment patients with bacterium-positive were higher than that of initial treatment patients,and the drug resistance rate of bacterium-positive PTB patients declined gradually with age. |
PDF Full Text Request