| Objective:To discuss the early necrosis-dispelling effect of Xinjiachilingsan external application dressing change on the postoperative wound surface from low simple anal fistula by studying the early necrosis-dispelling effect of Xinjiachilingsan dressing change and Vaseline gauze dressing change on the postoperative wound surface from low simple anal fistula and detailedly recording the postoperative wound surface secretions,granulation color,granulation density,wound surface vertical diameter healing rate,wound surface relative area reduction rate,wound surface pain and so on.Research methods:40 patients with low anal fistula admitted to the Anorectal Surgery Department of Nanjing Traditional Chinese Medicine Hospital of the Chinese Traditional Chinese Medicine Anorectal Disease Centre from December 2018 to December 2018 were chosen and randomly divided into experimental group(Xinjiachilingsan dressing change,20 cases in total)and a control group(sterilized Vaseline oil gauze dressing change,20 cases in total),the two groups of patient were compared to each other on day 2,4,6 and 10 after operation in terms of postoperative wound secretions,granulation color,granulation density,wound surface depth,wound vertical diameter healing rate,relative area reduction rate of the wound surface,and the postoperative wound surface pain grading,and the time required for the full recovery of wound was recorded,the overall curative effect was evaluated on week 5 after operation.The SPSS 22.0 statistical software was used to analyze the indexes of Xinjiachilingsan dressing change and the Vaseline gauze dressing change related to the low simple anal fistula in the early stage after operation.The data were analyzed and compared to evaluate the clinical efficacy of Xinjiachilingsan external application dressing change method.Result:A total of 40 subjects were included in the experiment,all of them have finished the experiment,including 20 cases for the experimental group and the control group each.In terms of the overall curative efficacy,the cure rate was 100%in both groups,and the difference was not statistically significant(P>0.05).The amount of exudation of the two groups was compared with that of the control group on day 2 after operation,and it was found that P= 0.770,no significant difference was noted(P>0.05),while on day 4,6,and 10 after surgery it was found P was less than 0.05 when compared with the control group.The difference was statistically significant;There was no significant difference in the score of granulation color between the two groups of patient on day 2 after operation(P>0.05),no statistical significance was noted.On day 4,6 and 10 after operation,the P of wound surface granulation color score was 0.01,0.004,and 0.024,respectively,P<0.05,the dif-ference was statistically significant.As compared with the control group,the degree of granulation density of the wound of the patients in the experimental group was not significantly different from that of the patients in the control group on the day 2 after operation(P>0.05);On the day 4,6,and 10 after operation,the P value of the granulation density of the wound surface was 0.003,0.001 and 0 respectively,and the difference was statistically significant(P<0.05);as compared with the.control group,The difference in pain score on day 2,4,6 and 10 after operation between the patients in experimental group and the ones in control group was statistically significant(P<0.05).There was no significant dif-ference in the wound surface vertical diameter healing rate between the experimental group and the control group on day 2 and 4 after operation(P>0.05);Their wound vertical diameter healing rate on day 6 and 10 after operation was evidently higher than that of the control group,the difference was statistically significant(P<0.05).There was no significant difference in the relative area reduction rate of the wound surface between the experimental group and the control group on day 2 and 4 after operation(P>0.05);There was a significant difference in the relative area reduction rate of the wound surface between the experimental group and the control group on day 6 and 10 after operation(P<0.05);On the 6th and 10th postoperative day,the relative area of the wounds was reduced.The difference was statistically significant compared with the control group(P<0.05).Compared with the control group,the total time necessary for the wound healing of the experimental group was significantly shorter than that of the control group,and the difference was statistically significant(P<0.05);During the clinical observation period,neither of the two groups of patient were found to have perianal allergies or systemic allergies and other discomfort symptoms when they received Xinjiachilingsan dressing change and Vaseline gauze dressing change.Conclusion:when Xinjiachilingsan is applied to the wound surface of low simple anal fistula,it can significantly reduce the wound exudation,and relieve the pain of patient caused by dressing change,having an obvious effect of dispelling necrosis and promoting fresh tissue,shortening the healing time of wound,and it has been shown that,a safe and effective TCM mixing of drug not only has a good clinical efficacy,but also is safe and easy to use when applied to the open anorectal wound. |
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