Effect Of Low-frequency Repetitive Transcranial Magnetic Stimulation Combined With Upper Limb Rehabilitation Robot On Upper Limb Motor Function In Stroke Patients With Hemiplegia

BackgroundStroke is a disease of brain tissue damage caused by local blood circulation disorder in the brain,and is one of the most important causes of death and disability.Survivors will have varying degrees of dysfunction including cognitive dysfunction,speech swallowing dysfunction,motor dysfunction,etc.Among them,upper limb motor dysfunction,as one of its main sequelae,has the characteristics of slow and complex rehabilitation process.The current training methods for upper limb dysfunction are mainly various types of exercise therapy,but the method has the disadvantages of time-consuming,energy-consuming,and boring mode.Therefore,the rehabilitation of upper limb motor function is a difficult problem and hot spot in the world of rehabilitation.Repetitive transcranial magnetic stimulation(rTMS)is a non-invasive,painless,non-invasive,and safe brain stimulation technique that can effectively improve the upper limb function of patients by regulating and intervening brain function.It has become one of the focuses of stroke rehabilitation,and low-frequency rTMS treatment has the advantages of good patient tolerance and high therapeutic safety,and is applied more clinically.The upper limb rehabilitation robot combines the emerging intelligent products in many fields such as rehabilitation medicine and mechanical engineering.It is a new non-invasive assisted rehabilitation technology that is safe,quantitative,effective and repetitive training.It has also become a research in the field of rehabilitation.hot spot.The combination of these two non-invasive assisted rehabilitation methods for the recovery of upper limb motor function after stroke is not reported at home and abroad.In this study,low-frequency rTMS and upper limb rehabilitation robots were combined to treat patients with upper extremity dysfunction after stroke to explore the clinical efficacy of this combination therapy in upper limb dysfunction after stroke.ObjectivesTo explore the effectiveness and safety of low-frequency rTMS combined with upper limb rehabilitation robot for rehabilitation of hemiplegia upper limb motor function:in patients with stroke recovery.Objects and methodsForty-five stroke hospitalized patients who met the inclusion criteria in the Department of Rehabilitation Medicine,Neurology,and Neurosurgery of Zhujiang Hospital of Southern Medical University were randomly divided into low-frequency rTMS group,rehabilitation robot group and combined group.Each group received routine treatment including drugs.Basic rehabilitation treatment.The low-frequency rTMS group was given low-frequency rTMS(1Hz)treatment on this basis,once a day,5 times a week for 4 weeks;the rehabilitation robot group was given upper limb rehabilitation robot training once a day,5 times a week for a total of 4 treatments.Week;the combined group on the basis of conventional treatment to increase low-frequency rTMS treatment and upper limb rehabilitation robot training,once a day,5 times a week for a total of 4 weeks,respectively,before treatment,4 weeks after treatment for each patient Assessment of upper extremity motor function and daily living ability,including Fugl-Meyer motor function assessment upper limb(UFMA),Hong Kong version of hemiplegic upper limb function test(FTHUE-HK)and modified Barthel index(MBI),measuring the patient’s hemiplegia Recovery of upper limb motor function.Statistical methodsStatistical analysis was performed using SPSS 19.0 statistical software.The sample data was expressed in the form of(x±s).Counting data for chi-square test,One-way ANOVA was used to compare the measurement data groups.If there is a significant difference,multiple comparisons are performed using the LSD-t test;Paired t-test was used before and after treatment in the group,and.The statistically significant test level was set at 0.05.ResultsThere were no significant differences in general data,UFMA score,FTHUE-HK grade,MBI score and difference between the three groups before treatment(P>0.05).After 4 weeks of treatment,the UFMA score,FTHUE-HK grade,and MBI score of the three groups were significantly higher than those before treatment(P<0.05),while the UFMA score and FTHUE-HK grade after treatment in the combination group were significantly better than the low-frequency rTMS group or the rehabilitation robot group(P<0.05),and the MBI scores between the groups after treatment were not significantly different(P>0.05).Conclusion1.Low-frequency rTMS combined with upper limb rehabilitation robot can safely and effectively promote the recovery of upper limb motor function in patients with stroke recovery.The therapeutic effect is more significant than single low-frequency rTMS treatment or upper limb rehabilitation robot training.2.The low-frequency rTMS combined with the upper limb rehabilitation robot is not superior to the single low-frequency rTMS treatment or upper-limb rehabilitation robot training in improving the daily living ability of patients with upper extremity motor dysfunction after stroke.