The Effect Of High Frequency Repetitive Transcranial Magnetic Stimulation On Cognitive Function Of Patients With Moderate Traumatic Brain Injury

BackgroundTraumatic brain injury(TBI)is a common and frequently-occurring disease in neurosurgery.It refers to the organic damage of brain tissue caused by external force on the head.With the continuous improvement of the social and economic level,the popularization and application of high-speed vehicles,the rapid development of the construction industry,and various intense sports programs,the incidence of craniocerebral injury continues to increase.Current literature studies have shown that cognitive dysfunction is one of the most common sequelae after craniocerebral injury.At present,the treatment of cognitive dysfunction after craniocerebral injury is mainly based on drug therapy and assists cognitive function exercise,and transcranial magnetic stimulation is an emerging treatment method that integrates safety,painlessness and non-invasiveness.And confirmed by domestic and foreign literature studies,can improve the cognitive function of patients,especially for speech,self-awareness,adaptive adjustment,executive function,etc.,but it is less used in patients with brain injury.This study selected patients with moderate craniocerebral injury as the research object,focusing on the therapeutic effect of transcranial magnetic stimulation on cognitive impairment in patients with moderate craniocerebral injury.ObjectiveTo explore the value of high frequency repetitive transcranial magnetic stimulation in patients with cognitive dysfunction after moderate traumatic brain injury MethodsThe patients with traumatic brain injury admitted to our hospital from October 2016 to October 2017 were selected as subjects.After admission,72 patients with moderate traumatic brain injury were selected according to the Glasgow Coma Index(GCS)score,according to the inclusion criteria.And exclusion criteria,a total of 40 subjects who met the criteria were collected.The cognitive function of the patients was assessed by the Montreal cognitive as-sessment(MoCA)and the modified Barthel index(MBI)around 7 days after injury,and were randomly divided into the control group and the stimulation group.Both groups were treated with conventional drug therapy and rehabilitation training.The stimulation group was given 15 Hz repetitive transcranial magnetic stimulation(rTMS)in the dorsolateral area of the left prefrontal lobe for a total of 4 weeks.Both groups were evaluated for cognitive function using MoCA and MBI scores before and 4 weeks after treatment.ResultsThere was no significant difference between the three groups in age,sex,years of education(P> 0.05).There was no significant difference in the MoCA and MBI scores between the two groups before treatment(P> 0.05),which was comparable;After 4 weeks of treatment,the MoCA and MBI scores of the two groups were increased differently than before treatment.In the comparison between groups,the treatment group was more significantly improved than the control group after 4 weeks of treatment,and the difference between the two groups was Statistical significance(P<0.05)ConclusionsrTMS can effectively improve the cognitive function and daily living ability of patients with moderate traumatic brain injury,and it has high therapeutic safety and is worthy of popularization in clinical practice.