| Objective: To measure the volume,density,meridian,length and CT enhancement of pancreas in type II diabetes mellitus by 256 slice spiral CT,and to compare the relationship between the volume,density,length and CT enhancement of pancreas in type II diabetes mellitus.Methods: The clinical and imaging data of 298 patients with type II diabetes mellitus and 406 healthy controls were analyzed retrospectively.Then the correlation analysis was made between the menstrual line density volume and fasting blood glucose body mass index(bmi),)course of body mass index(BMI)age and so on in type II diabetes mellitus patients.Results: The pancreatic density in the head,body and tail of the experimental group(34.23 ±15.22 hu,38.17 ±13.89 Hu,38.53±11.15 Hu)was significantly lower than that of the healthy control group(46.50 ±8.39 hu,46.64 ±7.72 hu,46.19 ±6.08hu).The pancreatic volume in the experimental group(49.34 ±14.47 cm ~ 3)was significantly lower than that in the control group(63.5418.48 cm ~ 3)(p < 0.05).The bmi index of the experimental group(24.46 ±3.23)was higher than that of the control group(23.40 ±3.02),and that of the experimental group(1.62 ±0.41 cm,1.45 ±0.45 cm)was lower than that of the control group(1.90±0.43 cm,1.58 ±0.46 cm).The pancreatic volume in the insulin treatment group(55.19±18.08 cm3,50.16 ±11.49 cm3,43.69 ±14.16 cm3)was significantly lower than that in the healthy control group(63.54 ±18.48 cm3),p < 0.05;there was a significant difference between the two groups in diet control,drug therapy and insulin treatmentgroup(55.19 ±18.08 cm3 ±11.49 cm3,43.69 ±14.16 cm3).Pancreatic volume in the experimental group was negatively correlated with age,course of disease and blood glucose(p < 0.05),and pancreatic density in the experimental group was negatively correlated with age,course of disease and blood glucose(p < 0.05).The pancreatic volume in the diabetic group and the healthy group increased with the increase of age.The pancreatic volume in the healthy control group reached the peak at the age of 40 and 50(70.51 ±19.57 cm3),and then decreased gradually with the increase of the age.The pancreatic volume of the experimental group reached a peak at 30 ~ 40 years old(6.28 ±11.88 cm ~ 3),which was earlier than that of the healthy control group,and then decreased gradually with the increase of age.The CT values(34.23 ±15.22,82.34±22.64 hu,84.85 ±18.59 hu,74.66 ±17.64 Hu)of the pancreas in the diabetic group were(46.50 ±8.39),88.61 ±16.83 huand 97.28 ±14.71 hurespectively,which were significantly higher than those in the healthy control group(46.50 ±8.39,88.61±16.83 huand 97.28 ±14.71 Hu,respectively).75.58 ±9.98 Hu)decreased;From 1 to 10 years,the ctvalues of pancreatic arterial phase,venous phase and delayed phase(83.24±24.56 hu,92.95 ±18.51 hu,74.33± 17.55hu)were lower than those of patients with disease duration ≤ 1 year(89.33 ±25.77 hu,98.56 ±22.39 hu,81.33 ±15.26 Hu).The ctvalue of arterial phase,venous phase and delayed phase(93.54 ±15.26 hu,106.63±12.65 Hu,88.45± 17.18 Hu)increased in the patients with the course of disease > 10 years.Conclusion:There is a correlation between the meridian,density and volume of pancreas in diabetic patients and the healthy control group,especially the density and volume of pancreas in type I diabetic patients.The pancreatic density and volume in type I diabetic patients are lower than those in the healthy control group,and with the development of the disease,The greater the effect of the course of disease on pancreatic density and volume,is an important index to influence the progress of diabetes mellitus,and the display of pancreatic morphological changes by multi-slice spiral ct is more intuitive,clear,direct and objective to clinicians.A comprehensive assessment of theseverity of diabetes patients points to a new path. |
PDF Full Text Request